{"id":"W2051131155","doi":"10.1038/ni.3132","title":"Senataxin suppresses the antiviral transcriptional response and controls viral biogenesis","year":2015,"lang":"en","type":"article","venue":"Nature Immunology","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McMaster University Medical Centre","funders":"National Cancer Institute; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; U.S. Public Health Service; National Institutes of Health","keywords":"Biology; Biogenesis; Virus; Virology; Influenza A virus; Gene; RNA; Amyotrophic lateral sclerosis; Ataxia; Orthomyxoviridae; Genetics; Medicine; Neuroscience; Disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004983574,0.0001203257,0.0001262535,0.00005041139,0.0001044315,0.00003117797,0.0002252009,0.00036519,0.000006917459],"category_scores_gemma":[0.0004692262,0.00008170908,0.0000548944,0.00006356264,0.0002878322,0.000006378018,0.00009047672,0.0003225775,0.000007369868],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001083439,"about_ca_system_score_gemma":0.0001192669,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000376387,"about_ca_topic_score_gemma":0.00002954504,"domain_scores_codex":[0.9988791,0.0003561978,0.0001177125,0.0002408014,0.000128725,0.0002774341],"domain_scores_gemma":[0.9994763,0.00007032041,0.00003253842,0.0002578213,0.0001100593,0.00005295308],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003366233,0.00002149521,0.001125797,0.000002201993,0.00008928739,0.00001058895,0.00002897764,0.000001556126,0.9912355,0.0006379557,0.00234977,0.001130626],"study_design_scores_gemma":[0.003095933,0.001124823,0.05897951,0.000008217561,0.00002438046,0.0002276384,0.0002630364,0.00006064525,0.6488542,0.0003506718,0.2867536,0.0002573149],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9782733,0.01788145,0.00009772464,0.003203096,0.000185909,0.0001441632,0.00005773683,0.00001073775,0.0001458487],"genre_scores_gemma":[0.9977986,0.0002373338,0.0001098029,0.0005564493,0.0001344125,0.00001772954,0.00006152014,0.00001232853,0.001071867],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3423813,"threshold_uncertainty_score":0.3332,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009420628918682875,"score_gpt":0.2684438469587826,"score_spread":0.2590232180400997,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}