{"id":"W2051152078","doi":"10.1111/pan.12468","title":"Identifying a rapid bolus dose of dexmedetomidine (<scp>ED</scp>50) with acceptable hemodynamic outcomes in children","year":2014,"lang":"en","type":"article","venue":"Pediatric Anesthesia","topic":"Anesthesia and Sedative Agents","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Dexmedetomidine; Medicine; Anesthesia; Hemodynamics; Bolus (digestion); Heart rate; Mean arterial pressure; Loading dose; Blood pressure; Sedative; Adverse effect; Sedation; Surgery; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000527059,0.0003896881,0.0009669159,0.0005149303,0.00008537409,0.0000286298,0.000303386,0.0001768883,0.00008230085],"category_scores_gemma":[0.0001955426,0.0002990802,0.0001797274,0.0007064906,0.0001001224,0.0002331305,0.00004529002,0.0002960885,0.0001031169],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007998283,"about_ca_system_score_gemma":0.0001535581,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002453846,"about_ca_topic_score_gemma":0.00001002828,"domain_scores_codex":[0.997543,0.0001513813,0.0006047566,0.0005205487,0.0005870204,0.0005932334],"domain_scores_gemma":[0.9984811,0.0002887261,0.0003510499,0.0005425266,0.0001065046,0.0002301068],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00008270039,0.0003681429,0.9969315,0.0001261296,0.00006604156,0.0001029728,0.0003359163,0.00002395876,0.0001700143,0.00009995,0.0003821907,0.001310478],"study_design_scores_gemma":[0.002160477,0.0004076542,0.9948204,0.00003706378,0.0003616376,0.0005980064,0.0001850181,0.0004262268,0.0003637372,0.00006052502,0.0004198976,0.0001593306],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971508,0.0007032765,0.0005067175,0.0001876782,0.00002154225,0.0007315849,0.000001765679,0.00009174846,0.0006048813],"genre_scores_gemma":[0.9958386,0.000347951,0.002059438,0.000456112,0.0001923515,0.00004616146,0.00005005727,0.00007363839,0.0009356749],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002111079,"threshold_uncertainty_score":0.9999461,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01022305730628134,"score_gpt":0.2447861565838484,"score_spread":0.2345630992775671,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}