{"id":"W2051192904","doi":"10.1016/j.ijrobp.2008.04.075","title":"Final Report of Multicenter Canadian Phase III Randomized Trial of 3 Versus 8 Months of Neoadjuvant Androgen Deprivation Therapy Before Conventional-Dose Radiotherapy for Clinically Localized Prostate Cancer","year":2008,"lang":"en","type":"article","venue":"International Journal of Radiation Oncology*Biology*Physics","topic":"Prostate Cancer Diagnosis and Treatment","field":"Medicine","cited_by":116,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ottawa Hospital; Northeast Cancer Centre; Ottawa Regional Cancer Foundation; Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Radiation therapy; Prostate cancer; Hormonal therapy; Androgen deprivation therapy; Flutamide; Prostate-specific antigen; Urology; Randomized controlled trial; Clinical endpoint; Goserelin; Prostate; Internal medicine; Cancer; Surgery; Oncology; Androgen receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003263222,0.001900807,0.003498082,0.0002889864,0.001302014,0.001701385,0.001923369,0.002390056,0.01056433],"category_scores_gemma":[0.003666498,0.0008654288,0.003495042,0.0007519793,0.001772141,0.0009223128,0.0004475747,0.00495066,0.001523522],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005773673,"about_ca_system_score_gemma":0.01269798,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.114814,"about_ca_topic_score_gemma":0.3077827,"domain_scores_codex":[0.9986015,0.0006130811,0.00007916706,0.0002551108,0.0001652369,0.0002859449],"domain_scores_gemma":[0.9976377,0.0005651346,0.0003457336,0.0002073989,0.0003129394,0.0009310598],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9807369,0.002311619,0.0003892756,0.0003079591,0.001393005,0.00001914396,0.00005020164,0.0003151106,0.001617969,0.0001258998,0.003698904,0.009034104],"study_design_scores_gemma":[0.9624959,0.02840846,0.003546038,0.00005580516,0.00177041,0.00002029728,0.00004329864,0.0002361821,0.000403728,0.000243204,0.002742299,0.00003432123],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9172567,0.01523449,0.0029302,0.009295384,0.005148528,0.01276203,0.0181916,0.0005388026,0.01864219],"genre_scores_gemma":[0.9492945,0.006333707,0.006241613,0.006909814,0.001361994,0.00585866,0.008087152,0.0001669939,0.01574558],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.114814,"threshold_uncertainty_score":0.2282915,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04516176082384848,"score_gpt":0.394761322091656,"score_spread":0.3495995612678075,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}