{"id":"W2051192904","doi":"10.1016/j.ijrobp.2008.04.075","title":"Final Report of Multicenter Canadian Phase III Randomized Trial of 3 Versus 8 Months of Neoadjuvant Androgen Deprivation Therapy Before Conventional-Dose Radiotherapy for Clinically Localized Prostate Cancer","year":2008,"lang":"en","type":"article","venue":"International Journal of Radiation Oncology*Biology*Physics","topic":"Prostate Cancer Diagnosis and Treatment","field":"Medicine","cited_by":116,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ottawa Hospital; Northeast Cancer Centre; Ottawa Regional Cancer Foundation; Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Radiation therapy; Prostate cancer; Hormonal therapy; Androgen deprivation therapy; Flutamide; Prostate-specific antigen; Urology; Randomized controlled trial; Clinical endpoint; Goserelin; Prostate; Internal medicine; Cancer; Surgery; Oncology; Androgen receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009842954,0.0001921669,0.001265455,0.000205688,0.00004692787,0.000004432893,0.0001825694,0.0001836414,0.00007160306],"category_scores_gemma":[0.0005531681,0.0001501346,0.0006533575,0.0001164004,0.0004032341,0.0001364924,0.0000127348,0.0001677402,3.531168e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006840718,"about_ca_system_score_gemma":0.002513025,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001637334,"about_ca_topic_score_gemma":0.0002175522,"domain_scores_codex":[0.9969539,0.0002008546,0.00211253,0.0002172954,0.0003276974,0.000187729],"domain_scores_gemma":[0.9935148,0.0007429363,0.003440183,0.0001602054,0.001991624,0.0001502361],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8070012,0.00245675,0.08049549,0.00002078265,0.004052359,0.0000751752,0.0009399711,0.0003810945,0.001468026,0.0006317238,0.0003923665,0.102085],"study_design_scores_gemma":[0.9686773,0.009159938,0.003358965,0.0001263102,0.0003742003,0.0000770628,0.00003518905,0.002582055,0.00765328,0.0006866499,0.007155256,0.0001137595],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9880063,0.001598657,0.003540396,0.002063811,0.002059066,0.00225679,0.0004289064,0.000007131286,0.00003894386],"genre_scores_gemma":[0.9847505,0.009525103,0.004010234,0.0002656162,0.000753431,0.0001952786,0.0004451458,0.00002431256,0.00003038818],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1616761,"threshold_uncertainty_score":0.612231,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04516176082384848,"score_gpt":0.394761322091656,"score_spread":0.3495995612678075,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}