{"id":"W2051218014","doi":"10.1074/jbc.m502454200","title":"Inhibition of Cellular HIV-1 Protease Activity by Lysyl-tRNA Synthetase","year":2005,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"","keywords":"Biology; Protease; Infectivity; Reverse transcriptase; RNA; Virus; Cell biology; Transfer RNA; Molecular biology; Virology; Biochemistry; Enzyme; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002211069,0.0003766975,0.0002842953,0.0001376822,0.0001156273,0.0004436887,0.0002082039,0.0002184071,0.0007859808],"category_scores_gemma":[0.0002279503,0.0001138194,0.000179849,0.0001199457,0.0002256596,0.0001307595,0.0001792697,0.0004867215,0.0002968099],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000304557,"about_ca_system_score_gemma":0.0002240422,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002948632,"about_ca_topic_score_gemma":0.0005623868,"domain_scores_codex":[0.9997854,0.00006952706,0.00002476814,0.00002524124,0.00004853401,0.0000466415],"domain_scores_gemma":[0.9998462,0.00005712478,0.00003554943,0.00002468706,0.0000118855,0.00002456391],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002452698,0.0000702829,0.0000992346,0.00003593032,0.00000562228,0.00002547321,0.000006382871,0.000110289,0.9974613,0.0001013294,0.00002878925,0.001810137],"study_design_scores_gemma":[0.00002255654,0.000529842,0.0004198725,0.000002688928,0.000005122972,0.00006201272,0.000004435356,0.000465252,0.9975943,0.00001985608,0.0008723276,0.000001678508],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920598,0.003794692,0.002228717,0.0001188656,0.00003793678,0.00002649048,0.0002034303,0.000113953,0.001416016],"genre_scores_gemma":[0.9938471,0.001486111,0.002753432,0.00003863758,0.00001622454,0.00003168465,0.0003588897,0.0000142297,0.001453693],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007859808,"threshold_uncertainty_score":0.00262934,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01632350291735178,"score_gpt":0.2482287076702788,"score_spread":0.231905204752927,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}