{"id":"W2051236844","doi":"10.1016/j.mvr.2011.05.008","title":"LYP, a bestatin dimethylaminoethyl ester, inhibited cancer angiogenesis both in vitro and in vivo","year":2011,"lang":"en","type":"review","venue":"Microvascular Research","topic":"Peptidase Inhibition and Analysis","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"Calgary Laboratory Services; University of Calgary","funders":"National Natural Science Foundation of China; Natural Science Foundation of Shandong Province; Calgary Laboratory Services; University of Calgary","keywords":"Angiogenesis; Matrigel; In vivo; Umbilical vein; Vascular endothelial growth factor; Basic fibroblast growth factor; Trypan blue; Chemistry; In vitro; Molecular biology; Endothelial stem cell; Neovascularization; Biology; Biochemistry; Growth factor; Cancer research","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002693946,0.0007697758,0.0009871714,0.0008467933,0.0001271813,0.0004013267,0.0004134458,0.0004332087,0.001413886],"category_scores_gemma":[0.0001670996,0.0002068031,0.0003149384,0.0007757192,0.0002554357,0.0004598165,0.0002483409,0.001190601,0.001011127],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003806193,"about_ca_system_score_gemma":0.0004218465,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008982144,"about_ca_topic_score_gemma":0.00173015,"domain_scores_codex":[0.9999355,0.000007497898,0.000007465426,0.00001182179,0.00002472635,0.00001297999],"domain_scores_gemma":[0.999941,0.00001747178,0.0000137178,0.000002541013,0.00001644179,0.000008866401],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005244374,0.0002489349,0.0002032452,0.00742145,0.0001461443,0.0003305865,0.00003746752,0.0007373832,0.0687702,0.001736259,0.01223472,0.9076092],"study_design_scores_gemma":[0.0003203145,0.001706331,0.003841537,0.001181358,0.0004829974,0.003191494,0.00006134033,0.0006337624,0.0922273,0.001153665,0.8951204,0.00007939301],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003900302,0.9916255,0.001133951,0.0002333198,0.0001411746,0.0000225044,0.00009341479,0.00003993063,0.002809917],"genre_scores_gemma":[0.01451007,0.97956,0.001060966,0.000260242,0.00007434437,0.00002513526,0.0002171583,0.00000716892,0.00428492],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001413886,"threshold_uncertainty_score":0.004729927,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1449353943907059,"score_gpt":0.431272486909647,"score_spread":0.286337092518941,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}