{"id":"W2051250848","doi":"10.1074/jbc.m111.314609","title":"Biochemical Analysis of Matrix Metalloproteinase Activation of Chemokines CCL15 and CCL23 and Increased Glycosaminoglycan Binding of CCL16","year":2011,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Chemokine receptors and signaling","field":"Medicine","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Centre for Blood Research, University of British Columbia; Michael Smith Health Research BC","keywords":"Chemokine; Proteases; Matrix metalloproteinase; Proteolysis; Chemistry; Cathepsin G; Chemotaxis; Biochemistry; Glycosaminoglycan; Cell biology; Immunology; Receptor; Biology; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003395335,0.0007416634,0.0002329125,0.0008783432,0.0001906966,0.0003191716,0.0001876177,0.0003336348,0.002616588],"category_scores_gemma":[0.000410497,0.000127699,0.000631852,0.0005511261,0.0002289887,0.0002098189,0.0002033279,0.0004783139,0.0005900669],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003017411,"about_ca_system_score_gemma":0.0002696519,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000555152,"about_ca_topic_score_gemma":0.0006933179,"domain_scores_codex":[0.9996684,0.00003583411,0.000035077,0.00006059317,0.0001232666,0.00007700623],"domain_scores_gemma":[0.9995475,0.00006056216,0.0001560493,0.00003353695,0.00009152125,0.0001107851],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001662267,0.00001658698,0.001821947,0.00007397249,0.00001906657,0.0002030014,0.00002748921,0.00001705959,0.9964498,0.0000203132,0.00001982453,0.001164692],"study_design_scores_gemma":[0.00002682015,0.0004009594,0.06360683,0.00002624893,0.00008241279,0.00331858,0.00008882982,0.0004711591,0.9296618,0.00006467236,0.002236324,0.00001539517],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9894421,0.004875841,0.003309189,0.00007260289,0.00003175205,0.00007771204,0.001324657,0.00004784095,0.0008183912],"genre_scores_gemma":[0.9861406,0.001824338,0.007365031,0.00007350632,0.00002086906,0.0001211845,0.002725368,0.00001965619,0.001709415],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002616588,"threshold_uncertainty_score":0.008753359,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03245069734916795,"score_gpt":0.2708266168250577,"score_spread":0.2383759194758898,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}