{"id":"W2051301499","doi":"10.1139/o08-137","title":"Effect of oxidative stress on the expression of t-PA, u-PA, u-PAR, and PAI-1 in endothelial cells","year":2008,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Blood Coagulation and Thrombosis Mechanisms","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Plasminogen activator; Umbilical vein; Oxidative stress; Plasminogen activator inhibitor-1; Sodium nitroprusside; Molecular biology; Nitric oxide; Urokinase; Biology; Fibrinolysis; Gene expression; Chemistry; Urokinase receptor; Endocrinology; Internal medicine; Gene; Biochemistry; Medicine; In vitro","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002177308,0.0002640769,0.0002280285,0.0001366045,0.0001519864,0.0002986567,0.0001018761,0.0002183101,0.0007207947],"category_scores_gemma":[0.0001883074,0.0001075721,0.0002679078,0.0001033661,0.0001719774,0.0002229776,0.0001101597,0.000384503,0.0001253956],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001321257,"about_ca_system_score_gemma":0.0001150898,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004878662,"about_ca_topic_score_gemma":0.0004729024,"domain_scores_codex":[0.9998357,0.00004348905,0.000016734,0.00003629836,0.00003200223,0.0000358023],"domain_scores_gemma":[0.999862,0.00003436268,0.00003465872,0.0000179559,0.00002935207,0.00002174998],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002540901,0.00005025275,0.0005275429,0.00006416922,0.00001456604,0.00006144556,0.00003730485,0.00003217818,0.9973077,0.00003406464,0.00001784724,0.001598918],"study_design_scores_gemma":[0.00002043632,0.001011267,0.0109317,0.000009687031,0.00004025645,0.0002622013,0.00008879816,0.00059158,0.9854705,0.00007020775,0.001495447,0.000007932803],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991791,0.005764566,0.001553069,0.00009727729,0.00005458667,0.00002056094,0.0001257236,0.00001769542,0.0005755327],"genre_scores_gemma":[0.9939626,0.003059981,0.001692383,0.00009682899,0.0000354879,0.00003138302,0.0002261721,0.000004393827,0.0008906912],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007207947,"threshold_uncertainty_score":0.002411306,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01200907549052963,"score_gpt":0.2446011346008152,"score_spread":0.2325920591102855,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}