{"id":"W2051302667","doi":"10.1007/s10059-011-2316-4","title":"Identification of Novel Subregions of LOH in Gastric Cancer and Analysis of the HIC1 and TOB1 Tumor Suppressor Genes in These Subregions","year":2011,"lang":"en","type":"article","venue":"Molecules and Cells","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"National Institute on Alcohol Abuse and Alcoholism; Canadian Institutes of Health Research","keywords":"Biology; Loss of heterozygosity; Molecular biology; Downregulation and upregulation; Gene; Immunohistochemistry; Methylation; Microarray analysis techniques; Chromosome; Gene silencing; Cancer; Tumor suppressor gene; Carcinogenesis; Western blot; Genetics; Cancer research; Gene expression; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001249773,0.00006703746,0.0001484361,0.0001127082,0.00001275236,0.000003668572,0.00006463099,0.00004890019,0.00000206453],"category_scores_gemma":[0.00001472159,0.00005303401,0.00004047341,0.0002455068,0.0001209793,0.000002826901,0.00005675021,0.00002790254,1.182147e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002520585,"about_ca_system_score_gemma":0.00001819522,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006061582,"about_ca_topic_score_gemma":0.0007783113,"domain_scores_codex":[0.9994304,0.00003707644,0.0002432133,0.0001568517,0.00005660431,0.00007584342],"domain_scores_gemma":[0.9995978,0.00001399582,0.0001533287,0.0001647008,0.00004846034,0.00002172666],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001845465,0.00006995804,0.1087973,0.00002711765,0.0000402614,1.940332e-7,0.0002991259,0.0001512911,0.8900331,0.00008901385,0.000001132086,0.0004730921],"study_design_scores_gemma":[0.0001917938,0.00003051309,0.3683618,0.00001113725,0.00008065445,2.982565e-7,0.00009865077,0.0007594987,0.6303631,0.00004677878,0.00001638243,0.00003938415],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994643,0.004437603,0.000682948,0.00002817173,0.00001387967,0.0001043243,0.00005961442,4.858309e-7,0.00002992563],"genre_scores_gemma":[0.9974001,0.00236746,0.0001733095,0.000008318791,0.000003713758,0.00000808955,0.000008090986,0.000004928066,0.00002597036],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.25967,"threshold_uncertainty_score":0.2162664,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01897031843617238,"score_gpt":0.24337176321003,"score_spread":0.2244014447738576,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}