{"id":"W2051349866","doi":"10.1016/j.clim.2008.03.069","title":"OR.63. B Cell Depletion in Multiple Sclerosis Results in Diminished Th1 and ThIL-17 Responses by CD4 and CD8 T Cells","year":2008,"lang":"en","type":"article","venue":"Clinical Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Multiple sclerosis; Cd4 t cell; CD8; Immunology; Cytotoxic T cell; T cell; Chemistry; Medicine; Cell biology; Biology; Immune system; Genetics; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000302319,0.0005408615,0.000745399,0.000645869,0.0003574671,0.0003991969,0.0002946679,0.0006891802,0.002448187],"category_scores_gemma":[0.0002293757,0.0003745037,0.0003604637,0.0003011585,0.0005118503,0.0004107383,0.0002758958,0.001535978,0.001412376],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001891178,"about_ca_system_score_gemma":0.000291732,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007282763,"about_ca_topic_score_gemma":0.001207816,"domain_scores_codex":[0.9996244,0.00005146674,0.00004655436,0.00003755511,0.00008541135,0.0001545734],"domain_scores_gemma":[0.9997851,0.00003414291,0.00003887636,0.0000290368,0.00001939632,0.00009347538],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001355076,0.0002312073,0.0002589856,0.00004867337,0.00001361911,0.0002302387,0.00002525139,0.00005296546,0.9953251,0.00010181,0.000168731,0.002188269],"study_design_scores_gemma":[0.0005092913,0.00290963,0.02367902,0.00003909553,0.0001158878,0.002205726,0.0001335546,0.001103672,0.9650988,0.0004443066,0.003744746,0.00001633681],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951823,0.001397168,0.0005975685,0.0002318482,0.00008578892,0.00002047817,0.0002808094,0.0000957817,0.002108271],"genre_scores_gemma":[0.9927571,0.0008823719,0.0007814181,0.000183734,0.00005495863,0.00006082536,0.0004837531,0.00004797199,0.004747939],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002448187,"threshold_uncertainty_score":0.008190036,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07400456614999401,"score_gpt":0.2942779160059634,"score_spread":0.2202733498559694,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}