{"id":"W2051395127","doi":"10.1074/jbc.m410337200","title":"Estrogen-related Receptor α (ERRα) Is a Transcriptional Regulator of Apolipoprotein A-IV and Controls Lipid Handling in the Intestine","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":107,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal; McGill University","funders":"Canadian Institutes of Health Research","keywords":"Nuclear receptor; Coactivator; Knockout mouse; Biology; Endocrinology; Apolipoprotein B; Lipid metabolism; Internal medicine; Estrogen-related receptor alpha; Receptor; Estrogen receptor; Chemistry; Biochemistry; Cholesterol; Gene; Transcription factor; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004874195,0.0001592323,0.0002867238,0.0000244314,0.00003917764,0.00001273909,0.0002203712,0.0003709556,0.00002459091],"category_scores_gemma":[0.0002538699,0.00009433923,0.0001869544,0.0001056643,0.000224351,0.00000535031,0.00003077904,0.0003829861,8.671274e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001853261,"about_ca_system_score_gemma":0.00008346365,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005803566,"about_ca_topic_score_gemma":2.310996e-7,"domain_scores_codex":[0.998895,0.00006523091,0.0005235545,0.000178721,0.0001505583,0.0001869554],"domain_scores_gemma":[0.9993433,0.00004106819,0.0002989793,0.0001321819,0.00009580549,0.00008871136],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000398974,0.0001515641,0.001879168,0.00002361333,0.00008165415,0.0000124541,0.00007350239,0.00004827232,0.9967052,0.0001690616,0.0000358632,0.0004206839],"study_design_scores_gemma":[0.00291113,0.000874549,0.002299672,0.0001435868,0.00003365613,0.0006559985,0.000133384,0.00001612252,0.990985,0.0005285101,0.001274005,0.0001444086],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907073,0.008171711,0.00008074372,0.0007573189,0.00004414689,0.0001193403,0.00001223009,0.000003284661,0.0001039654],"genre_scores_gemma":[0.9983951,0.0006034616,0.0006138331,0.0001277204,0.0002071458,0.000005058217,0.00001730285,0.000007882628,0.00002249493],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007687842,"threshold_uncertainty_score":0.3847042,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01027490927925928,"score_gpt":0.2301822352067603,"score_spread":0.219907325927501,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}