{"id":"W2051485743","doi":"10.1016/j.molimm.2009.10.026","title":"Mycophenolic acid differentially affects dendritic cell maturation induced by tumor necrosis factor-α and lipopolysaccharide through a different modulation of MAPK signaling","year":2010,"lang":"en","type":"article","venue":"Molecular Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":14,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"University of Toronto","keywords":"MAPK/ERK pathway; Cell biology; Tumor necrosis factor alpha; Phosphorylation; Signal transduction; Kinase; Cytokine; Lipopolysaccharide; Chemistry; Extracellular; Biology; Immunology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001190508,0.0002836358,0.0002642706,0.0001810583,0.0001698024,0.0002758611,0.0001535407,0.0003705213,0.001035727],"category_scores_gemma":[0.0001728629,0.0001455812,0.0002938395,0.0001591746,0.0002115269,0.0002959743,0.000178638,0.0004908008,0.0002538471],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002352323,"about_ca_system_score_gemma":0.0002614327,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003830286,"about_ca_topic_score_gemma":0.0004439883,"domain_scores_codex":[0.999822,0.00003971263,0.00001520967,0.00002614137,0.00003050968,0.00006648699],"domain_scores_gemma":[0.9998956,0.00001678717,0.00002386116,0.00001261577,0.00002021795,0.00003092434],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001102241,0.00002545384,0.0001371405,0.00002410886,0.000005188857,0.0000535201,0.000008043929,0.00001525497,0.9978582,0.00006397434,0.00001089862,0.0006959426],"study_design_scores_gemma":[0.00007334866,0.0004033863,0.006540828,0.000005633513,0.00003412969,0.0001442791,0.00003916467,0.0002279873,0.9914947,0.00008116255,0.0009502732,0.000005153392],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968535,0.001151467,0.0007133038,0.0000890134,0.00005426143,0.00001866709,0.000173705,0.00001873243,0.0009273348],"genre_scores_gemma":[0.9966398,0.000974494,0.000865418,0.00006659095,0.00002209098,0.00003272538,0.000188704,0.000007494755,0.001202715],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001035727,"threshold_uncertainty_score":0.003464818,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007279096198389537,"score_gpt":0.2088138980703654,"score_spread":0.2015348018719759,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}