{"id":"W2051579138","doi":"10.1016/j.mce.2007.01.009","title":"Probasin promoter assembles into a strongly positioned nucleosome that permits androgen receptor binding","year":2007,"lang":"en","type":"article","venue":"Molecular and Cellular Endocrinology","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; University of Victoria","funders":"National Cancer Institute; Terry Fox Foundation","keywords":"Nucleosome; Promoter; Histone; Molecular biology; Histone octamer; Androgen receptor; Chromatin; Biology; Electrophoretic mobility shift assay; DNA; Histone H3; Binding site; Chemistry; Gene; Transcription factor; Genetics; Gene expression; Prostate cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000295355,0.0002832991,0.0003225423,0.0002759189,0.0005462145,0.0006174751,0.0002948461,0.000372022,0.002366572],"category_scores_gemma":[0.0004026466,0.000517485,0.0003552504,0.000157692,0.000438488,0.0004581703,0.000814764,0.0007801905,0.001737792],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007907912,"about_ca_system_score_gemma":0.0004503782,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001696641,"about_ca_topic_score_gemma":0.004559023,"domain_scores_codex":[0.9996347,0.00002631601,0.00001333145,0.0001303537,0.000136351,0.00005889711],"domain_scores_gemma":[0.9997125,0.00004439955,0.00004930798,0.00003755319,0.00004078118,0.0001153693],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004919018,0.000006422113,0.0004771121,0.00001814264,0.000004544251,0.0001190738,0.00002867971,0.0000812407,0.9972282,0.0003309502,0.0001546999,0.001501734],"study_design_scores_gemma":[0.00001866921,0.00008252564,0.008249554,0.000006890519,0.000008229383,0.0006593884,0.00007228909,0.001761736,0.9804268,0.0003695232,0.008330685,0.00001379446],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9574751,0.00257539,0.03026135,0.0005875465,0.0002591576,0.00004103833,0.0004180366,0.0006300921,0.007752168],"genre_scores_gemma":[0.9799794,0.0003433923,0.0096419,0.0002248837,0.000070412,0.00002791135,0.000737465,0.0001325783,0.008842021],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002366572,"threshold_uncertainty_score":0.007916987,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007081506623715265,"score_gpt":0.2221711056182498,"score_spread":0.2150895989945346,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}