{"id":"W2051604556","doi":"10.1016/j.cell.2013.02.034","title":"Dynamic Integration of Splicing within Gene Regulatory Pathways","year":2013,"lang":"en","type":"review","venue":"Cell","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":413,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; National Human Genome Research Institute; Canadian Institutes of Health Research","keywords":"RNA splicing; Biology; Alternative splicing; Crosstalk; Splicing factor; Chromatin; Precursor mRNA; Regulation of gene expression; Genetics; Computational biology; Gene expression; Gene; Cell biology; Messenger RNA; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001208172,0.001399408,0.002066121,0.002103221,0.0004047102,0.001925913,0.001561154,0.001685144,0.001821559],"category_scores_gemma":[0.0008870461,0.0006434728,0.0004317313,0.003076159,0.00187548,0.00285567,0.001410957,0.002778543,0.001655833],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001389422,"about_ca_system_score_gemma":0.00131917,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009295717,"about_ca_topic_score_gemma":0.001817011,"domain_scores_codex":[0.9996786,0.00005115811,0.00004302003,0.0000838283,0.0001086123,0.00003477512],"domain_scores_gemma":[0.9995819,0.0002033313,0.00005423261,0.00002159219,0.00009939295,0.00003966774],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008926297,0.0000385042,0.0001721867,0.008016111,0.00007865089,0.0003050425,0.00006974172,0.0008600564,0.005122948,0.01838486,0.02158538,0.9452773],"study_design_scores_gemma":[0.00001417935,0.00003778326,0.0004341231,0.001374686,0.00007896591,0.001017047,0.00006338134,0.0002415323,0.001400776,0.009953984,0.9853558,0.00002761826],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001335689,0.996777,0.0009630487,0.0004076331,0.0004111922,0.000004157227,0.00001472248,0.00001419504,0.001274478],"genre_scores_gemma":[0.0007513275,0.9972311,0.0005644076,0.0002655397,0.0004881445,0.000005968186,0.00002867367,0.00000300634,0.0006618729],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002103221,"threshold_uncertainty_score":0.01008105,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02750826911885871,"score_gpt":0.2922773197366935,"score_spread":0.2647690506178347,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}