{"id":"W2051604556","doi":"10.1016/j.cell.2013.02.034","title":"Dynamic Integration of Splicing within Gene Regulatory Pathways","year":2013,"lang":"en","type":"review","venue":"Cell","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":413,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; National Human Genome Research Institute; Canadian Institutes of Health Research","keywords":"RNA splicing; Biology; Alternative splicing; Crosstalk; Splicing factor; Chromatin; Precursor mRNA; Regulation of gene expression; Genetics; Computational biology; Gene expression; Gene; Cell biology; Messenger RNA; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002398478,0.0002398983,0.000544193,0.00008660833,0.0000390827,0.00001868104,0.0002780748,0.0003402695,0.0000195241],"category_scores_gemma":[0.00003979666,0.000187924,0.0002614005,0.00009056123,0.00005735625,0.000002629737,0.0001203171,0.0002107323,0.00004276906],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003752447,"about_ca_system_score_gemma":0.0002184143,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002802405,"about_ca_topic_score_gemma":0.00001188693,"domain_scores_codex":[0.9987651,0.0000954826,0.000418827,0.0003479355,0.0001504504,0.0002222664],"domain_scores_gemma":[0.998968,0.00001352831,0.0002935743,0.0005525459,0.00008399474,0.0000883218],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000002790739,0.00001918286,3.066844e-7,0.002173364,0.00002761351,0.000001851767,0.00001194455,0.000003057807,0.685095,0.00001210979,0.0002991575,0.3123537],"study_design_scores_gemma":[0.0004257883,0.0005051928,0.00001008434,0.005778441,0.0002723103,0.00004417765,0.00009251495,0.0006863218,0.6193278,0.00005110768,0.3719147,0.0008915499],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02571323,0.9721891,0.0007185522,0.00000140577,0.0001073182,0.0004446105,0.00002232828,0.00000764372,0.0007958133],"genre_scores_gemma":[0.002069844,0.9902526,0.001282934,0.00001011081,0.00008697598,0.00004760094,0.0005426007,0.00004988907,0.005657443],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.3716155,"threshold_uncertainty_score":0.766332,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02750826911885871,"score_gpt":0.2922773197366935,"score_spread":0.2647690506178347,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}