{"id":"W2051640940","doi":"10.1128/aac.02425-13","title":"In Vitro and In Vivo Efficacy of Novel Flavonoid Dimers against Cutaneous Leishmaniasis","year":2014,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Cutaneous leishmaniasis; Leishmaniasis; Leishmania; Amastigote; Leishmania donovani; Leishmania tropica; Leishmania braziliensis; Visceral leishmaniasis; Flavonoid; Pharmacology; In vivo; In vitro; Biology; Immunology; Microbiology; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001729712,0.0002592477,0.0001467571,0.000128019,0.00007850142,0.00008856552,0.0001526926,0.0001786961,0.001670509],"category_scores_gemma":[0.0001104235,0.00006357376,0.0001702259,0.00007722162,0.0001036387,0.0001685491,0.00007089727,0.0002637061,0.0002973943],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001100739,"about_ca_system_score_gemma":0.00008725403,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003068796,"about_ca_topic_score_gemma":0.0003248781,"domain_scores_codex":[0.9999398,0.00002481036,0.000004456754,0.0000105853,0.000009846731,0.00001046999],"domain_scores_gemma":[0.9999485,0.000008522489,0.00001721071,0.00000616666,0.00001030789,0.000009386619],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004439743,0.0001164808,0.00009128401,0.0001186292,0.00001097368,0.00003275961,0.00001019333,0.000260459,0.9955799,0.0000941543,0.0001724047,0.003068746],"study_design_scores_gemma":[0.000151513,0.004687272,0.001995987,0.00001814735,0.00003182861,0.0002569126,0.00001714475,0.0007906479,0.9865797,0.00008105922,0.005382819,0.000006957582],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9842623,0.005705131,0.004155528,0.0002546152,0.0000638022,0.0001349017,0.0009280719,0.00009852576,0.00439708],"genre_scores_gemma":[0.9936038,0.001995094,0.002028289,0.0001266391,0.00001905199,0.00004528722,0.0007491274,0.00001212813,0.001420511],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001670509,"threshold_uncertainty_score":0.005588412,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01442752358422341,"score_gpt":0.2698373355711542,"score_spread":0.2554098119869308,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}