{"id":"W2051640940","doi":"10.1128/aac.02425-13","title":"<i>In Vitro</i> and <i>In Vivo</i> Efficacy of Novel Flavonoid Dimers against Cutaneous Leishmaniasis","year":2014,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Cutaneous leishmaniasis; Leishmaniasis; Leishmania; Amastigote; Leishmania donovani; Leishmania tropica; Leishmania braziliensis; Visceral leishmaniasis; Flavonoid; Pharmacology; In vivo; In vitro; Biology; Immunology; Microbiology; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002190836,0.0002377722,0.0006097025,0.0001893537,0.00005790498,0.00002552393,0.0001025775,0.0001045768,0.00002970309],"category_scores_gemma":[0.00004966163,0.0002100847,0.00008082791,0.0002236863,0.0002435367,0.00008488064,0.0000696909,0.0001958024,0.000002469997],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003758963,"about_ca_system_score_gemma":0.00002730433,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002181329,"about_ca_topic_score_gemma":0.00004863497,"domain_scores_codex":[0.9985548,0.00004073083,0.0003827253,0.0004195465,0.0001976463,0.000404605],"domain_scores_gemma":[0.9994065,0.0001079008,0.00009385881,0.000228918,0.00004841432,0.0001144165],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001371903,0.0009025132,0.02133661,0.0002091759,0.0001046611,0.00004676401,0.0007376454,0.000008088485,0.9551663,0.0000152111,0.008048835,0.01205229],"study_design_scores_gemma":[0.02778708,0.000543352,0.08233862,0.000583387,0.00006795621,0.0001663253,0.0002071842,0.001192914,0.8301743,0.0000179308,0.05623818,0.0006827876],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993112,0.00007042102,0.0000227038,0.004643213,0.00006261687,0.0004378288,0.00001787672,0.00001724239,0.001616105],"genre_scores_gemma":[0.9849764,0.004090175,0.000750161,0.009674756,0.00008142452,0.00000585965,0.000006544501,0.00003969487,0.000375029],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.124992,"threshold_uncertainty_score":0.8567007,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01442752358422341,"score_gpt":0.2698373355711542,"score_spread":0.2554098119869308,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}