{"id":"W2051693683","doi":"10.1371/journal.pone.0108595","title":"Expression of DP2 (CRTh2), a Prostaglandin D2 Receptor, in Human Mast Cells","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Mast cells and histamine","field":"Immunology and Microbiology","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; University of Alberta Hospital; University of Alberta","funders":"Alberta Innovates; Fondation pour la Recherche Médicale; University of Alberta; Alberta Innovates - Health Solutions; GlaxoSmithKline; Canadian Institutes of Health Research; AstraZeneca Canada; Canadian Lung Association; Canadian Allergy, Asthma and Immunology Foundation; AstraZeneca","keywords":"Prostaglandin D2; Flow cytometry; Receptor; Degranulation; Immune system; Intracellular; Biology; Cell biology; Cell culture; Pertussis toxin; Signal transduction; Immunology; Biochemistry; G protein; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001725142,0.000108993,0.0002991818,0.0001007964,0.00005848495,0.000004364867,0.0001331744,0.0001579256,0.002643867],"category_scores_gemma":[0.00002314304,0.00009646717,0.0000339753,0.00007424474,0.0000969988,0.0000326051,0.00006468089,0.0001849193,0.0002630356],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001604048,"about_ca_system_score_gemma":0.000009566392,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001019557,"about_ca_topic_score_gemma":0.00007353997,"domain_scores_codex":[0.9991604,0.0001150038,0.0002656652,0.000201741,0.00004059558,0.0002165719],"domain_scores_gemma":[0.9995528,0.00004437119,0.0001125465,0.0002382693,0.00003507116,0.00001691784],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008228239,0.001147832,0.005312181,0.0001285753,0.000026145,5.385238e-7,0.0004328505,5.314202e-7,0.9912435,0.0002898736,0.001143537,0.0001921855],"study_design_scores_gemma":[0.001228093,0.0002727068,0.001366189,0.000242866,0.00001962545,4.146225e-7,0.00004144232,0.000002889946,0.9864122,0.00005823289,0.01024318,0.0001121682],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924398,0.0003429863,0.00001939106,0.0000555626,0.00007767983,0.0002152119,0.00002585422,0.00002633229,0.006797175],"genre_scores_gemma":[0.9876071,0.00003553283,0.0003208373,0.00002659121,0.00002935123,0.00001875337,0.0001065773,0.00001387318,0.01184138],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009099646,"threshold_uncertainty_score":0.9982678,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01894953876483661,"score_gpt":0.203296767715747,"score_spread":0.1843472289509103,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}