{"id":"W2051702454","doi":"10.1080/15257770008033058","title":"Shape-Selective Binding of Geometrically-Constrained<i>bis</i>-Distamycins to a DNA Duplex and a Model Okazaki Fragment of Identical Sequence","year":2000,"lang":"en","type":"article","venue":"Nucleosides Nucleotides & Nucleic Acids","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Institute of General Medical Sciences; National Cancer Institute; Centers for Disease Control and Prevention","keywords":"Nucleic acid; Duplex (building); Okazaki fragments; DNA; Chemistry; Stereochemistry; Base pair; Binding site; HMG-box; Crystallography; DNA-binding protein; Biochemistry; DNA replication; Gene; Transcription factor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003865439,0.0005410594,0.0007547879,0.0002486307,0.0001688152,0.00008089914,0.0006825543,0.0003804246,0.0005561955],"category_scores_gemma":[0.0003811234,0.0005554814,0.0003054175,0.000712505,0.0007443475,0.00005266745,0.0003750402,0.0002822364,0.00003139677],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007241632,"about_ca_system_score_gemma":0.000164857,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004442485,"about_ca_topic_score_gemma":0.000009475318,"domain_scores_codex":[0.996577,0.00006460913,0.001037968,0.001001343,0.0005625166,0.0007565378],"domain_scores_gemma":[0.9981149,0.00007401512,0.0002917223,0.0007590848,0.0002733399,0.0004869742],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004030199,0.0002962128,0.002811049,0.0001493349,0.0001853851,0.00001294308,0.0003164914,0.0004540775,0.9805722,0.0004449011,0.0008461143,0.01350822],"study_design_scores_gemma":[0.002176089,0.001534201,0.007806395,0.0003263719,0.0002650837,0.0001438619,0.0006979922,0.009584011,0.9710615,0.0005151192,0.004633043,0.001256332],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993219,0.0002210181,0.0004375982,0.0001984103,0.00005291789,0.0004211971,0.0002135309,0.00005924669,0.005177056],"genre_scores_gemma":[0.988631,0.0002878275,0.009891109,0.0004762755,0.00009739235,0.00002388124,0.0000472953,0.0001074343,0.0004377645],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01225189,"threshold_uncertainty_score":0.9996896,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0114182872571142,"score_gpt":0.2510876339018237,"score_spread":0.2396693466447095,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}