{"id":"W2051702454","doi":"10.1080/15257770008033058","title":"Shape-Selective Binding of Geometrically-Constrained<i>bis</i>-Distamycins to a DNA Duplex and a Model Okazaki Fragment of Identical Sequence","year":2000,"lang":"en","type":"article","venue":"Nucleosides Nucleotides & Nucleic Acids","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Institute of General Medical Sciences; National Cancer Institute; Centers for Disease Control and Prevention","keywords":"Nucleic acid; Duplex (building); Okazaki fragments; DNA; Chemistry; Stereochemistry; Base pair; Binding site; HMG-box; Crystallography; DNA-binding protein; Biochemistry; DNA replication; Gene; Transcription factor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001106349,0.0003712003,0.000286398,0.00005180148,0.0001043219,0.0001930745,0.0002928743,0.0002678429,0.0009816259],"category_scores_gemma":[0.0003955914,0.0001302999,0.0001486002,0.00007776373,0.000235981,0.0001446064,0.0002166946,0.0002724901,0.0003502053],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000242904,"about_ca_system_score_gemma":0.00011189,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005539289,"about_ca_topic_score_gemma":0.001000113,"domain_scores_codex":[0.9998429,0.00004307847,0.00000923374,0.00003974718,0.00004077895,0.0000242729],"domain_scores_gemma":[0.999836,0.0000432227,0.00004837565,0.00001712914,0.00002173382,0.00003361644],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007580371,0.000009370875,0.0001215574,0.000038177,0.00000682301,0.00001233349,0.00001383966,0.0002311613,0.9987187,0.00004342779,0.00001592664,0.0007128363],"study_design_scores_gemma":[0.000007607352,0.0003032568,0.0009873228,0.00000348728,0.000007932566,0.00007775588,0.00002731345,0.0005812092,0.9971342,0.00001930486,0.0008439678,0.000006608751],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996102,0.0004990163,0.002289575,0.00001713977,0.00001007966,0.00001649608,0.00006975631,0.00002875591,0.0009672],"genre_scores_gemma":[0.9944462,0.0003601514,0.004019746,0.00003915063,0.000002498447,0.000020449,0.0001700402,0.00001967408,0.0009220782],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009816259,"threshold_uncertainty_score":0.003283858,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0114182872571142,"score_gpt":0.2510876339018237,"score_spread":0.2396693466447095,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}