{"id":"W2051721478","doi":"10.1016/j.biotechadv.2007.11.003","title":"Agrin and neuregulin, expanding roles and implications for therapeutics","year":2007,"lang":"en","type":"review","venue":"Biotechnology Advances","topic":"Toxin Mechanisms and Immunotoxins","field":"Immunology and Microbiology","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Agrin; Neuregulin; Synaptogenesis; Neuregulin 1; Neuroscience; Biology; Receptor; Cell biology; Signal transduction; Acetylcholine receptor; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006465861,0.001041672,0.001264144,0.001337211,0.0003289591,0.001223365,0.0009567687,0.001591943,0.002795009],"category_scores_gemma":[0.0006129763,0.0002721271,0.0002763897,0.001851006,0.0008542105,0.001845253,0.0006490567,0.002532169,0.001976357],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009130512,"about_ca_system_score_gemma":0.001082196,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009115296,"about_ca_topic_score_gemma":0.00230785,"domain_scores_codex":[0.9998102,0.00002389491,0.00001765507,0.00002792038,0.0001018446,0.00001860091],"domain_scores_gemma":[0.9997198,0.0001371471,0.00003299289,0.000008305558,0.00006414609,0.00003756307],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001881759,0.00009717423,0.00020111,0.006404344,0.00005061237,0.0005180037,0.00007421382,0.0005024411,0.007462774,0.01003018,0.05508398,0.919387],"study_design_scores_gemma":[0.00002259665,0.00004692997,0.0004283302,0.0007167813,0.00002953895,0.001213605,0.00006772063,0.00008260868,0.0005300564,0.003387393,0.9934632,0.00001118171],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001187372,0.9978017,0.0001539004,0.0004710416,0.0003536296,0.000002295872,0.000006645102,0.000005280182,0.001086884],"genre_scores_gemma":[0.0004969261,0.9974521,0.0002337956,0.0003431911,0.0003761731,0.00000453667,0.00001395692,9.872434e-7,0.001078353],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002795009,"threshold_uncertainty_score":0.00935024,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04506379595779913,"score_gpt":0.3506249556440216,"score_spread":0.3055611596862225,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}