{"id":"W2051806971","doi":"10.1371/journal.pone.0096597","title":"Intracellular Long-Chain Acyl CoAs Activate TRPV1 Channels","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Canadian Diabetes Association","keywords":"Chemistry; TRPV1; Intracellular; Biochemistry; Phosphatidylinositol; Cell biology; Phospholipid; Ion channel; Biophysics; Transient receptor potential channel; Biology; Receptor; Membrane; Signal transduction","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001501309,0.0003704253,0.0003535833,0.0001779858,0.0001681142,0.0003335098,0.0002058072,0.0004588127,0.003625268],"category_scores_gemma":[0.000280215,0.0001032176,0.0004666912,0.000183376,0.0002222211,0.0005113319,0.000527627,0.0006578402,0.0007828966],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003357721,"about_ca_system_score_gemma":0.0002211086,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004024921,"about_ca_topic_score_gemma":0.000547875,"domain_scores_codex":[0.9997618,0.00004453311,0.00001600795,0.0000371535,0.00005353686,0.00008701999],"domain_scores_gemma":[0.9998863,0.00003189136,0.00002300225,0.00001105889,0.00002082321,0.00002691896],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003369455,0.0000301156,0.0001287929,0.0001201397,0.000007081771,0.00007048168,0.00002238196,0.00003600085,0.9973219,0.0001677091,0.0001061873,0.001652221],"study_design_scores_gemma":[0.00006903946,0.0005553802,0.007213791,0.00003826454,0.00003112274,0.0002853189,0.0001212822,0.0007773557,0.9856833,0.0005697723,0.004641635,0.00001376017],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9639657,0.01426734,0.01137143,0.001065364,0.0003064379,0.0001183583,0.0008384936,0.0001786381,0.007888146],"genre_scores_gemma":[0.9875589,0.00439931,0.004120141,0.0003820232,0.00008792496,0.00008656115,0.0003264663,0.00002428926,0.003014239],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003625268,"threshold_uncertainty_score":0.01212776,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06183852638976325,"score_gpt":0.2315191846552451,"score_spread":0.1696806582654818,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}