{"id":"W2051806971","doi":"10.1371/journal.pone.0096597","title":"Intracellular Long-Chain Acyl CoAs Activate TRPV1 Channels","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Canadian Diabetes Association","keywords":"Chemistry; TRPV1; Intracellular; Biochemistry; Phosphatidylinositol; Cell biology; Phospholipid; Ion channel; Biophysics; Transient receptor potential channel; Biology; Receptor; Membrane; Signal transduction","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000246944,0.0001901908,0.0002716214,0.00009693825,0.0001987243,0.00007003337,0.0003168258,0.0001169766,0.0004108906],"category_scores_gemma":[0.0005353816,0.0001619401,0.0000696862,0.000238694,0.000114992,0.0001665087,0.0001051447,0.0002617563,0.0007829802],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000283501,"about_ca_system_score_gemma":0.00001683484,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001063845,"about_ca_topic_score_gemma":0.000001722505,"domain_scores_codex":[0.9982746,0.0001616802,0.0002110551,0.0004493949,0.0004669817,0.00043632],"domain_scores_gemma":[0.9992371,0.0001918359,0.0001042157,0.0002532759,0.00004160597,0.0001719303],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002577273,0.0007219733,0.00004456484,0.00004837853,0.00001456438,0.000009520088,0.0003199612,0.00005087191,0.9964006,0.000709879,0.0002497288,0.001404199],"study_design_scores_gemma":[0.0003623483,0.0001454269,0.00002093675,0.00008315257,0.00001961803,0.000003285596,0.00002040849,0.006536195,0.9906759,0.0005403552,0.001368878,0.000223543],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993946,0.00003193474,0.001086259,0.001703579,0.0006063799,0.0002840816,0.000006344649,0.0001882038,0.002147231],"genre_scores_gemma":[0.991233,0.00009584183,0.0001244548,0.0006899517,0.0007470503,0.00002761891,0.000003728162,0.00004142203,0.007036964],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006485323,"threshold_uncertainty_score":0.9999951,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06183852638976325,"score_gpt":0.2315191846552451,"score_spread":0.1696806582654818,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}