{"id":"W2051832959","doi":"10.1182/blood-2013-06-498303","title":"von Willebrand disease: advances in pathogenetic understanding, diagnosis, and therapy","year":2013,"lang":"en","type":"review","venue":"Blood","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":167,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research","keywords":"Von Willebrand disease; Von Willebrand factor; Desmopressin; Hemostasis; Platelet disorder; Missense mutation; Coagulopathy; Bleeding diathesis; Immunology; Medicine; Phenotype; Platelet; Genetics; Biology; Internal medicine; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004265735,0.0003201528,0.001110275,0.0001400464,0.0000384386,0.00002324943,0.00005498644,0.0001314105,0.00007977105],"category_scores_gemma":[0.00001822445,0.0002137725,0.0001481775,0.0001413547,0.00005118873,0.0000632023,0.00002070996,0.0001337954,0.00001883717],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003766497,"about_ca_system_score_gemma":0.00009026533,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007546154,"about_ca_topic_score_gemma":0.000009217659,"domain_scores_codex":[0.9989603,0.00005012157,0.0002608689,0.0003586618,0.000143019,0.0002270603],"domain_scores_gemma":[0.9994219,0.00008279036,0.0001038232,0.0002135401,0.000008623452,0.0001693256],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000117493,0.0008104851,0.01767278,0.005217987,0.0002083828,0.0006242857,0.00001736209,2.183678e-8,8.609359e-8,0.00003305942,0.00007088662,0.9753329],"study_design_scores_gemma":[0.004406002,0.0002276525,0.0009068386,0.01214706,0.0014119,0.00009635538,0.00001388614,3.976602e-7,7.337463e-7,0.0005738905,0.9799336,0.0002816381],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003197091,0.9948663,0.000001302532,0.00003110891,0.00004781754,0.001470915,0.0000482387,0.00002076306,0.0003164354],"genre_scores_gemma":[0.0006636415,0.9984057,0.00003436616,0.00003584258,0.00004188533,0.000546662,0.0001333234,0.00004336326,0.0000952199],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9798627,"threshold_uncertainty_score":0.8717389,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0502404870894125,"score_gpt":0.3211771857562363,"score_spread":0.2709366986668238,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}