{"id":"W2051839343","doi":"10.1210/er.2006-0001","title":"The Role of the IGF System in Cancer Growth and Metastasis: Overview and Recent Insights","year":2007,"lang":"en","type":"review","venue":"Endocrine Reviews","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":1002,"is_retracted":false,"has_abstract":true,"ca_institutions":"Royal Victoria Hospital; McGill University Health Centre; Royal Victoria Regional Health Centre","funders":"","keywords":"Effector; Context (archaeology); Malignancy; Cancer; Metastasis; Cancer research; Biology; Neuroscience; Receptor; Bioinformatics; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008242091,0.0006178028,0.003486433,0.0002055527,0.0001286775,0.0000285878,0.0003244646,0.0001355959,0.0000125373],"category_scores_gemma":[0.000349829,0.000266449,0.0005262249,0.0009996464,0.0001626373,0.00007665669,0.0002790968,0.0007384006,0.000009384732],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001736438,"about_ca_system_score_gemma":0.0002623193,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003267293,"about_ca_topic_score_gemma":0.0001319018,"domain_scores_codex":[0.9960908,0.000649134,0.001920479,0.0005094137,0.0003811595,0.000449071],"domain_scores_gemma":[0.9976951,0.0003129817,0.000925225,0.000794569,0.00009209449,0.0001800625],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000009883613,0.00003477114,0.0001426526,0.04351869,0.0001509242,0.00001293897,0.00006515215,3.581038e-9,0.00000159968,0.001552383,0.0002855927,0.9542254],"study_design_scores_gemma":[0.0003390475,0.00006234866,0.0002011902,0.04260987,0.001756836,0.000223962,0.00007166794,8.738344e-7,0.00003375783,0.00003025305,0.9544464,0.0002238271],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008711411,0.9934184,4.55509e-7,0.0001232863,0.0002700664,0.003409942,0.00002294455,0.00001817852,0.002649587],"genre_scores_gemma":[0.000181506,0.9989088,0.00003602189,0.0001073935,0.0001780754,0.0004033464,0.00001347807,0.00005775237,0.0001136649],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9541607,"threshold_uncertainty_score":0.9999788,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08536394265762687,"score_gpt":0.3677728423925343,"score_spread":0.2824088997349075,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}