{"id":"W2051890221","doi":"10.1016/j.celrep.2015.03.005","title":"The Nuclear Oncogene SET Controls DNA Repair by KAP1 and HP1 Retention to Chromatin","year":2015,"lang":"en","type":"article","venue":"Cell Reports","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":93,"is_retracted":false,"has_abstract":true,"ca_institutions":"Beatrice Hunter Cancer Research Institute; Dalhousie University","funders":"National Health and Medical Research Council; Medical Research Council; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Agence Nationale de la Recherche; General Secretariat for Research and Technology; Fondation ARC pour la Recherche sur le Cancer; Institut National Du Cancer; Human Frontier Science Program; European Molecular Biology Organization; Fondation pour la Recherche Médicale; Centre National de la Recherche Scientifique; Schlumberger Foundation","keywords":"Chromatin; Heterochromatin; DNA damage; Cell biology; DNA repair; Biology; Histone; DNA; Homologous recombination; Molecular biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006393833,0.000126056,0.0001227376,0.00001308234,0.00009839926,0.00004373817,0.00007884436,0.0001184688,0.000006968764],"category_scores_gemma":[0.0002166042,0.00009986774,0.00007415321,0.00004239195,0.000039845,0.000003572462,0.0001346585,0.00004924284,0.00001517392],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000222825,"about_ca_system_score_gemma":0.00005133604,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001675004,"about_ca_topic_score_gemma":0.000008988019,"domain_scores_codex":[0.9988919,0.00006251416,0.0002756826,0.0003850212,0.0001745786,0.000210321],"domain_scores_gemma":[0.9989785,0.000008443179,0.0001578094,0.0005682568,0.00008840465,0.0001986078],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003503817,0.0000178264,0.0001032429,0.000006191814,0.00001872904,0.00005077297,0.00004573941,0.000002528139,0.916136,0.00001152077,0.08296423,0.0006082151],"study_design_scores_gemma":[0.0002229676,0.0003201925,0.00006125653,0.000006054698,0.00001752874,0.0001640519,0.0001102963,0.00005292523,0.5663598,0.0001412919,0.4324201,0.000123515],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934382,0.0009735941,0.0001213071,0.0001754144,0.0002827737,0.0003382844,0.000007027029,0.00005558617,0.004607744],"genre_scores_gemma":[0.9927011,0.00005363665,0.0007893638,0.0003323345,0.0001090494,0.00002526384,0.00006656664,0.00003111847,0.00589163],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3497762,"threshold_uncertainty_score":0.4072488,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01016584349313556,"score_gpt":0.2256302234648437,"score_spread":0.2154643799717081,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}