{"id":"W2051897756","doi":"10.1002/pbc.22165","title":"Treatment of children with acute promyelocytic leukemia: Results of the first North American intergroup trial INT0129","year":2009,"lang":"en","type":"article","venue":"Pediatric Blood & Cancer","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"National Cancer Institute","keywords":"Medicine; Acute promyelocytic leukemia; Blood cancer; Induction therapy; Internal medicine; Toxicity; Retinoic acid; Induction chemotherapy; Complete remission; Randomized controlled trial; Overall survival; Maintenance therapy; Chemotherapy; Oncology; Cancer; Surgery; Gastroenterology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003956952,0.000665939,0.001096052,0.0003123441,0.0003443698,0.000709644,0.0006282922,0.0007789421,0.001381605],"category_scores_gemma":[0.002126777,0.0002144074,0.001195381,0.0004792755,0.0005164162,0.000553855,0.0004086975,0.001822434,0.0002359202],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000970288,"about_ca_system_score_gemma":0.001521231,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00187343,"about_ca_topic_score_gemma":0.00552587,"domain_scores_codex":[0.9985831,0.001039551,0.00006496316,0.00007946711,0.0001339089,0.00009896635],"domain_scores_gemma":[0.9983778,0.0004728175,0.000463568,0.0001360633,0.00006849066,0.0004813006],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.6918169,0.0211984,0.06061672,0.001550604,0.00442639,0.0004349588,0.0005909305,0.002342693,0.007160557,0.000775233,0.01304652,0.1960401],"study_design_scores_gemma":[0.5068461,0.2659473,0.1877183,0.0006917871,0.004989315,0.001465347,0.0004275345,0.001007804,0.00365304,0.0005209249,0.02664967,0.00008281292],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9742643,0.01778669,0.000317878,0.001895524,0.0001465411,0.0006182196,0.001951836,0.00004159866,0.002977326],"genre_scores_gemma":[0.977755,0.008808476,0.00164277,0.001955187,0.0002781178,0.001040812,0.006593302,0.00003773465,0.001888606],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003956952,"threshold_uncertainty_score":0.02092665,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004690691625779666,"score_gpt":0.2263235508155131,"score_spread":0.2216328591897334,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}