{"id":"W2052132396","doi":"10.1021/pr900481b","title":"Proteomic Analysis of Src Family Kinases Signaling Complexes in Golgi/Endosomal Fractions Using a Site-Selective Anti-Phosphotyrosine Antibody: Identification of LRP1-Insulin Receptor Complexes","year":2009,"lang":"en","type":"article","venue":"Journal of Proteome Research","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Endosome; Golgi apparatus; LRP1; Proto-oncogene tyrosine-protein kinase Src; Kinase; Chemistry; Cell biology; Phosphorylation; Insulin receptor; Receptor tyrosine kinase; Antibody; Biochemistry; Receptor; Biology; Insulin; Genetics; LDL receptor; Endocrinology; Cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001874359,0.0005244614,0.0003775013,0.0005653953,0.0002764748,0.0003047152,0.0002233563,0.000271753,0.0007817981],"category_scores_gemma":[0.0001398609,0.0001824626,0.0003676015,0.0003198464,0.0001417533,0.0002277764,0.0002779997,0.0004462698,0.0004662563],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002385615,"about_ca_system_score_gemma":0.0002146385,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006320694,"about_ca_topic_score_gemma":0.0008398243,"domain_scores_codex":[0.9998615,0.00001326082,0.00001259235,0.00004192516,0.00003861049,0.00003205302],"domain_scores_gemma":[0.9999074,0.0000156632,0.00002261945,0.000006785609,0.00002321671,0.00002426236],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004499105,0.000009085023,0.0002814927,0.00003880232,0.000009063475,0.00004710985,0.00001413448,0.00001727761,0.9988045,0.00001838376,0.00001726544,0.000697976],"study_design_scores_gemma":[0.00001554022,0.0001835902,0.03930743,0.00002380354,0.00008128798,0.001513377,0.0001151546,0.002352761,0.9533277,0.00008502488,0.002980406,0.00001393516],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9878622,0.002589481,0.008006347,0.00009656733,0.00002275576,0.00003326855,0.000667423,0.00006546328,0.0006565598],"genre_scores_gemma":[0.9616376,0.005248105,0.02516115,0.0001894912,0.00003913831,0.00009323105,0.003717209,0.00008392272,0.003830176],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007817981,"threshold_uncertainty_score":0.002615392,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04596980992029679,"score_gpt":0.3641452602321598,"score_spread":0.318175450311863,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}