{"id":"W2052132396","doi":"10.1021/pr900481b","title":"Proteomic Analysis of Src Family Kinases Signaling Complexes in Golgi/Endosomal Fractions Using a Site-Selective Anti-Phosphotyrosine Antibody: Identification of LRP1-Insulin Receptor Complexes","year":2009,"lang":"en","type":"article","venue":"Journal of Proteome Research","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Endosome; Golgi apparatus; LRP1; Proto-oncogene tyrosine-protein kinase Src; Kinase; Chemistry; Cell biology; Phosphorylation; Insulin receptor; Receptor tyrosine kinase; Antibody; Biochemistry; Receptor; Biology; Insulin; Genetics; LDL receptor; Endocrinology; Cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001752056,0.0001486259,0.0005432995,0.001143731,0.0001154319,0.00003408497,0.0002518879,0.0001531356,0.0000233066],"category_scores_gemma":[0.0002050004,0.0001419063,0.0003020874,0.001705095,0.0001741399,0.00003529611,0.00003002386,0.0003935253,9.204944e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008458431,"about_ca_system_score_gemma":0.0002718471,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002854,"about_ca_topic_score_gemma":0.00003126607,"domain_scores_codex":[0.9974143,0.0003163068,0.001052686,0.0002679093,0.0006528649,0.000295962],"domain_scores_gemma":[0.9976982,0.00004380388,0.0007170679,0.0002364864,0.001224516,0.00007996015],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007058848,0.000442562,0.02099704,0.00006497898,0.0002663386,0.000007111139,0.0001788883,0.003714442,0.9734701,0.00001776761,0.000005226324,0.0001296345],"study_design_scores_gemma":[0.0006161312,0.0006445746,0.1680759,0.0001228874,0.0001254391,0.000006087434,0.0001677921,0.002271998,0.8277442,0.00007530369,0.00004349146,0.0001062688],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9747618,0.000864736,0.02361579,0.00007257672,0.00003251194,0.0005666283,0.00006837733,0.000002968763,0.00001454103],"genre_scores_gemma":[0.9963174,0.0003548104,0.002642645,0.00000618722,0.00009091049,0.000006275907,0.0005541766,0.00001417171,0.00001343777],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1470788,"threshold_uncertainty_score":0.5786773,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04596980992029679,"score_gpt":0.3641452602321598,"score_spread":0.318175450311863,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}