{"id":"W2052140198","doi":"10.1097/mph.0b013e318184e6b3","title":"Prostaglandin Inhibitors in the Treatment of Single-system Langerhans Cell Histiocytosis: Pharmacologic Rationale and Report of Two Cases","year":2008,"lang":"en","type":"article","venue":"Journal of Pediatric Hematology/Oncology","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Pediatric Oncology Group","funders":"","keywords":"Medicine; Langerhans cell histiocytosis; Prostaglandin; Clinical trial; Histiocytosis; Prostaglandin antagonist; Prostaglandin E1; Pharmacology; Internal medicine; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005402665,0.00135716,0.001140494,0.001880472,0.001240954,0.001145515,0.001216632,0.005925368,0.001049762],"category_scores_gemma":[0.001943669,0.00057838,0.001127326,0.001254637,0.001950274,0.001421519,0.0007832827,0.003632646,0.0007313699],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009700707,"about_ca_system_score_gemma":0.0007623985,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001340223,"about_ca_topic_score_gemma":0.001306579,"domain_scores_codex":[0.9993788,0.00009395413,0.0001280431,0.0001190222,0.000114559,0.0001655061],"domain_scores_gemma":[0.998888,0.0004456156,0.0002951618,0.0001266978,0.00006691081,0.0001776285],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.0001133545,0.0001349603,0.003692019,0.0003685321,0.00005174497,0.9701352,0.0003778371,0.0003043458,0.002069597,0.001505295,0.001438162,0.01980891],"study_design_scores_gemma":[0.00002577254,0.00008376736,0.001364905,0.00004853986,0.00003860583,0.9928325,0.00006538022,0.0001225463,0.001268147,0.000193005,0.003940197,0.00001657282],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5465966,0.3598452,0.02596007,0.01933058,0.002870308,0.000670966,0.0006950212,0.000915665,0.04311557],"genre_scores_gemma":[0.8935218,0.08342694,0.006171674,0.005638386,0.003555387,0.0001496925,0.0002805675,0.00008791942,0.007167731],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005925368,"threshold_uncertainty_score":0.007038355,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05232019073086424,"score_gpt":0.3258481425058539,"score_spread":0.2735279517749896,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}