{"id":"W2052145627","doi":"10.1016/j.bbalip.2010.12.012","title":"Purification and characterization of a second type of neutral ceramidase from rat brain: A second more hydrophobic form of rat brain ceramidase","year":2011,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Emirates Foundation; H2020 European Research Council; Fondation pour la Recherche Médicale; Terry Fox Foundation; Medical University of South Carolina","keywords":"Biochemistry; Chemistry; Enzyme; Sphingosine; Ceramide; Glycosylation; Chromatography; Glycan; Substrate (aquarium); Molecular mass; Stereochemistry; Glycoprotein; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003823371,0.001040635,0.0006640637,0.0005244188,0.0002388248,0.0006160667,0.0004986473,0.0004518804,0.0009122538],"category_scores_gemma":[0.0005403676,0.0002606137,0.0008343911,0.0003628506,0.0003531688,0.0006142474,0.0005129637,0.001008423,0.0008776903],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006405474,"about_ca_system_score_gemma":0.000582893,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001172623,"about_ca_topic_score_gemma":0.001024735,"domain_scores_codex":[0.9998065,0.00001744956,0.00002569155,0.00004050388,0.00004455635,0.00006527689],"domain_scores_gemma":[0.9995121,0.00006585875,0.0000800561,0.00007935239,0.00012269,0.0001398877],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002130893,0.00002050837,0.0001654273,0.00003798465,0.00001078128,0.0001052068,0.00001708693,0.00003770436,0.9983202,0.0000921265,0.00003172011,0.0009480951],"study_design_scores_gemma":[0.0000689756,0.0003202542,0.005851634,0.00001171007,0.00005565597,0.001626609,0.00006808293,0.0007287558,0.9867851,0.0001597309,0.004303033,0.00002055604],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9794807,0.00342323,0.01415508,0.0003835421,0.0001035198,0.0001097866,0.001120287,0.00007339259,0.00115043],"genre_scores_gemma":[0.9589509,0.003403608,0.02186637,0.0002741641,0.0001118947,0.0001873231,0.007679783,0.00009495373,0.007430999],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001172623,"threshold_uncertainty_score":0.004647493,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01138662335988663,"score_gpt":0.2296915572939594,"score_spread":0.2183049339340728,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}