{"id":"W2052165289","doi":"10.1016/j.joca.2015.01.002","title":"A new prescription for growth? Statins, cholesterol and cartilage homeostasis","year":2015,"lang":"en","type":"letter","venue":"Osteoarthritis and Cartilage","topic":"Connective tissue disorders research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Achondroplasia; Fibroblast growth factor receptor; Dwarfism; Genetics; Medicine; Internal medicine; Endocrinology; Biology; Receptor; Fibroblast growth factor; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002273142,0.0003829002,0.0004010793,0.000104452,0.0001319829,0.0002057872,0.0001692873,0.0006344807,0.0000300445],"category_scores_gemma":[0.0001853645,0.0004161172,0.0001115425,0.00007236098,0.0001400762,0.00001649576,0.0002182277,0.0003689509,0.00000697528],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002358,"about_ca_system_score_gemma":0.0001632336,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006913637,"about_ca_topic_score_gemma":0.0006062668,"domain_scores_codex":[0.9979017,0.0001355133,0.0002758793,0.0008330539,0.0003065673,0.0005472331],"domain_scores_gemma":[0.9989669,0.00003288281,0.0001073159,0.0003947012,0.0002780662,0.0002201121],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001248433,0.00001096081,0.000144787,0.0002493413,0.00001283397,0.00003859712,0.0002017533,1.238128e-7,0.1862856,0.000009714219,0.7657135,0.04720798],"study_design_scores_gemma":[0.002469471,0.001553373,0.00005193558,0.00008516855,0.00006001195,0.00005885308,0.0001683757,0.000001068704,0.06031487,0.0003107635,0.9344418,0.0004842909],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8454967,0.07207958,0.0006111959,0.0734757,0.0005094333,0.003329035,0.002722984,0.00006680064,0.001708549],"genre_scores_gemma":[0.6405752,0.01839781,0.002545611,0.2372656,0.01430748,0.002966441,0.01895016,0.001143596,0.06384815],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2049215,"threshold_uncertainty_score":0.9998291,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01703307240946896,"score_gpt":0.2638781220611507,"score_spread":0.2468450496516817,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}