{"id":"W2052169804","doi":"10.1038/nsmb.1534","title":"Histone H3 tail clipping regulates gene expression","year":2008,"lang":"en","type":"article","venue":"Nature Structural & Molecular Biology","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":183,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval; Hôtel-Dieu de Québec","funders":"Canadian Institutes of Health Research; Wellcome Trust","keywords":"Histone H3; Nucleosome; Biology; Histone H2A; Histone code; Histone; Histone methylation; Promoter; SAP30; Histone methyltransferase; Cell biology; Genetics; Molecular biology; Gene expression; Gene; DNA methylation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00008186164,0.0003359398,0.0002929686,0.00007358896,0.0002426617,0.00001351115,0.0004198494,0.0009818646,0.00003716611],"category_scores_gemma":[0.00008945059,0.0002934563,0.0001982179,0.0001130857,0.0002483498,0.000004290259,0.0002763309,0.000430008,0.000007172452],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004042653,"about_ca_system_score_gemma":0.00007861393,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001234315,"about_ca_topic_score_gemma":0.000006092221,"domain_scores_codex":[0.9983148,0.000104128,0.0003154874,0.0006773193,0.0001259345,0.0004623243],"domain_scores_gemma":[0.9989591,0.000007521561,0.0001714997,0.0006063752,0.0001317422,0.0001237944],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005391693,0.000008836129,0.000946096,0.000009129358,0.00005098528,0.00003191719,0.0000292985,0.0001210327,0.9968252,0.0006555783,0.000658898,0.0006091389],"study_design_scores_gemma":[0.0006152545,0.0002068414,0.004100848,0.000009052799,0.0000181134,0.0004971409,0.0000138244,0.0002019965,0.9843951,0.001486535,0.008022149,0.0004330737],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907811,0.005818951,0.001928853,0.0002278841,0.0005846052,0.0001923322,0.00004359498,0.0000357123,0.000386952],"genre_scores_gemma":[0.9855371,0.0002088043,0.01171364,0.0008638509,0.0003095042,0.0000117551,0.0009579914,0.0000471771,0.0003501649],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01243,"threshold_uncertainty_score":0.9999518,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0036518443406423,"score_gpt":0.258845680295072,"score_spread":0.2551938359544297,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}