{"id":"W2052169804","doi":"10.1038/nsmb.1534","title":"Histone H3 tail clipping regulates gene expression","year":2008,"lang":"en","type":"article","venue":"Nature Structural & Molecular Biology","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":183,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval; Hôtel-Dieu de Québec","funders":"Canadian Institutes of Health Research; Wellcome Trust","keywords":"Histone H3; Nucleosome; Biology; Histone H2A; Histone code; Histone; Histone methylation; Promoter; SAP30; Histone methyltransferase; Cell biology; Genetics; Molecular biology; Gene expression; Gene; DNA methylation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001429453,0.000259202,0.0002704954,0.0002398807,0.0004195055,0.0009264987,0.0002858611,0.0003556074,0.003521658],"category_scores_gemma":[0.0001442629,0.000336247,0.0003747533,0.0002016861,0.0003922803,0.000317798,0.0005696667,0.0009380731,0.001326963],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007385105,"about_ca_system_score_gemma":0.0002920063,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001369277,"about_ca_topic_score_gemma":0.003211957,"domain_scores_codex":[0.9998109,0.00001040652,0.000006817476,0.00005773628,0.00003347592,0.00008072449],"domain_scores_gemma":[0.9998286,0.00003410528,0.00002525456,0.00002212152,0.00001751302,0.00007236177],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001875087,0.00001720469,0.0002602876,0.00001333394,0.000005311304,0.00004363557,0.000008460691,0.00003616488,0.9973645,0.0001916027,0.0001959812,0.001676019],"study_design_scores_gemma":[0.00002702079,0.00005896808,0.01882037,0.000004758367,0.00001234841,0.0001314422,0.00004563241,0.001207617,0.976779,0.0001804393,0.00272468,0.00000777672],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9810053,0.00275288,0.006623077,0.0004473148,0.0002311378,0.00002303824,0.001167716,0.0005807584,0.007168855],"genre_scores_gemma":[0.9900912,0.0005129111,0.001045735,0.0001977456,0.00002844682,0.00001461811,0.001017497,0.0001104336,0.006981364],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003521658,"threshold_uncertainty_score":0.0117811,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0036518443406423,"score_gpt":0.258845680295072,"score_spread":0.2551938359544297,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}