{"id":"W2052184186","doi":"10.1016/j.jcjd.2012.07.060","title":"High Levels of Glucose Cause Cell Cycle Arrest and Modify Wnt Signalling to Skew the Differentiation of Mesenchymal Progenitor Cells","year":2012,"lang":"en","type":"article","venue":"Canadian Journal of Diabetes","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Mesenchymal stem cell; Progenitor cell; Adipogenesis; Medicine; Cell biology; Wnt signaling pathway; Progenitor; Bone marrow; Cellular differentiation; Multipotent Stem Cell; Endogeny; Stem cell; Immunology; Biology; Signal transduction; Endocrinology; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007427975,0.0003218655,0.0002336677,0.0003636542,0.0002205536,0.0005946389,0.0001993629,0.0002351695,0.002680789],"category_scores_gemma":[0.0001145652,0.0001962176,0.0002800919,0.0003243824,0.0002570809,0.0001990333,0.0002378889,0.0006715981,0.0003945557],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006173006,"about_ca_system_score_gemma":0.0004738902,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004433761,"about_ca_topic_score_gemma":0.01186368,"domain_scores_codex":[0.9998587,0.00001557271,0.000009967172,0.00001752394,0.00003480508,0.00006328307],"domain_scores_gemma":[0.9999093,0.00001359716,0.00001952319,0.000009781075,0.00001145819,0.00003633144],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004378885,0.00004866383,0.000506275,0.00002225221,0.000008920112,0.00006002829,0.00001453526,0.00006701252,0.9967181,0.0001985608,0.0001512023,0.00176655],"study_design_scores_gemma":[0.0000576491,0.000399143,0.02124681,0.00001137851,0.00003304667,0.0001838107,0.0001286162,0.000524756,0.9733193,0.0002624205,0.003819738,0.00001321598],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907489,0.002789333,0.001326504,0.0005373608,0.0001603985,0.000017046,0.0008475083,0.00008036393,0.00349248],"genre_scores_gemma":[0.9931586,0.00166167,0.0008710293,0.0002449395,0.0000219031,0.00001870669,0.0005889777,0.00005375098,0.00338041],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004433761,"threshold_uncertainty_score":0.008968115,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01191508121309329,"score_gpt":0.2151554257677815,"score_spread":0.2032403445546882,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}