{"id":"W2052189229","doi":"10.1007/s00294-005-0020-7","title":"A mutation in yeast Tel1p that causes differential effects on the DNA damage checkpoint and telomere maintenance","year":2005,"lang":"en","type":"article","venue":"Current Genetics","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"G2-M DNA damage checkpoint; Biology; Telomere; Saccharomyces cerevisiae; DNA damage; Cell cycle checkpoint; Mutation; Telomere-binding protein; Cell biology; Genetics; DNA repair; CHEK1; Mutant; Gene; DNA; Cell cycle; DNA-binding protein","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008462161,0.0001716017,0.0001118387,0.0000383517,0.00004971747,0.00003351509,0.0001445623,0.00008043445,0.00001128415],"category_scores_gemma":[0.00006247589,0.0001284108,0.00004835729,0.00005536864,0.00006006644,0.00000280409,0.0001197515,0.0001215073,0.00001414426],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002202293,"about_ca_system_score_gemma":0.00002447335,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001579658,"about_ca_topic_score_gemma":0.0000461842,"domain_scores_codex":[0.9991013,0.00007430873,0.0001427608,0.0003078291,0.0001398059,0.0002339707],"domain_scores_gemma":[0.9995281,0.00002034071,0.00006494407,0.0003020303,0.00002598042,0.00005857189],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005559624,0.0001564756,0.002770866,0.00007460095,0.00002552843,0.000006242662,0.0002111959,0.00006878645,0.9288293,0.0003384268,0.0006935782,0.06676937],"study_design_scores_gemma":[0.0005938084,0.0001839017,0.02424617,0.00007708236,0.00001730799,0.000008700495,0.00005723972,0.0007761002,0.9674717,0.0001477584,0.006233926,0.0001863168],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997678,0.0009251945,0.0004305858,0.0002067956,0.0002753974,0.0003374778,0.0000134031,0.00001221236,0.0001209608],"genre_scores_gemma":[0.9987944,0.0004617367,0.0001897361,0.0001141207,0.0002489829,0.00004516735,0.00003309093,0.00002224411,0.0000904916],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06658305,"threshold_uncertainty_score":0.5236439,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01439709795550313,"score_gpt":0.2525596140205771,"score_spread":0.238162516065074,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}