{"id":"W2052228332","doi":"10.1016/j.cmet.2010.01.003","title":"A Macrophage Sterol-Responsive Network Linked to Atherogenesis","year":2010,"lang":"en","type":"article","venue":"Cell Metabolism","topic":"Atherosclerosis and Cardiovascular Diseases","field":"Immunology and Microbiology","cited_by":80,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; University of Washington","keywords":"Sterol; Cell biology; Biology; Apolipoprotein E; Apolipoprotein B; Cholesterol; Sterol regulatory element-binding protein; Phenotype; Macrophage; Microvesicles; Foam cell; Biochemistry; Lipoprotein; In vitro; Disease; Gene; microRNA; Medicine; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002173214,0.000272369,0.0002706172,0.0004542172,0.0002919507,0.0004654442,0.0002471631,0.000261941,0.0012131],"category_scores_gemma":[0.0001253618,0.0001448587,0.0002101089,0.0002327392,0.0002357732,0.0003182052,0.0004340854,0.0003092516,0.0003483576],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003156996,"about_ca_system_score_gemma":0.0002418857,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002517334,"about_ca_topic_score_gemma":0.0004234976,"domain_scores_codex":[0.9998796,0.00003013912,0.00000485851,0.00003109653,0.00002375918,0.00003052975],"domain_scores_gemma":[0.999898,0.00001523314,0.00002024731,0.00001147374,0.00002295906,0.00003202568],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006380457,0.00006053048,0.003087485,0.0001075928,0.00003414651,0.0003861526,0.00007956218,0.0006606453,0.9834313,0.003512846,0.000425084,0.007576637],"study_design_scores_gemma":[0.0001639674,0.001561964,0.1992734,0.0001818252,0.0004328498,0.002275057,0.001092512,0.01858138,0.7129838,0.03343636,0.02992305,0.00009376338],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9643988,0.006781013,0.0181149,0.001208646,0.00009227049,0.00008834438,0.0007003661,0.0002022478,0.008413375],"genre_scores_gemma":[0.990491,0.00199564,0.003280919,0.0002440862,0.00006640791,0.00005282335,0.0004754582,0.00001309564,0.003380645],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0012131,"threshold_uncertainty_score":0.004058242,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005996295127918031,"score_gpt":0.2050388174727007,"score_spread":0.1990425223447827,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}