{"id":"W2052229400","doi":"10.1111/j.1365-2141.2006.06237.x","title":"Significant increase of <i>CKS1B</i> amplification from monoclonal gammopathy of undetermined significance to multiple myeloma and plasma cell leukaemia as demonstrated by interphase fluorescence <i>in situ</i> hybridisation","year":2006,"lang":"en","type":"article","venue":"British Journal of Haematology","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"Cancer Research Society","keywords":"Monoclonal gammopathy of undetermined significance; Plasma cell dyscrasia; Multiple myeloma; Fluorescence in situ hybridization; Plasma cell neoplasm; Plasma cell; Plasma cell leukemia; Pathology; Molecular biology; Monoclonal; Medicine; Cancer research; Plasmacytoma; Biology; Monoclonal antibody; Internal medicine; Immunology; Antibody; Immunoglobulin light chain; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002982979,0.0001871311,0.0007964549,0.0002436154,0.00004040236,0.00002256304,0.0001637602,0.0001196963,0.00002256683],"category_scores_gemma":[0.0004428261,0.0002004726,0.0001006897,0.0002342539,0.000248479,0.0001515224,0.00003922682,0.0002508654,0.00000470032],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001143337,"about_ca_system_score_gemma":0.0003373479,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006410452,"about_ca_topic_score_gemma":0.0008249064,"domain_scores_codex":[0.9976397,0.0002199908,0.001134754,0.0003110142,0.0003885641,0.0003060303],"domain_scores_gemma":[0.9980781,0.000482897,0.0006428498,0.0001764971,0.0003334577,0.000286208],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003211604,0.001014679,0.1123407,0.0001322329,0.00005419226,0.00752838,0.00008102487,0.00001820513,0.8661647,0.00001448068,0.0007737699,0.008665936],"study_design_scores_gemma":[0.007625053,0.0008801438,0.1113167,0.0006434346,0.00008816415,0.008075487,0.0001710005,0.000843831,0.8699839,0.0001612261,0.00005045541,0.0001606239],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997227,0.000791231,0.0008822996,0.000132418,0.00004518281,0.0005190108,0.0002529256,0.000009005959,0.0001409427],"genre_scores_gemma":[0.9953296,0.0002024724,0.004195508,0.0000377744,0.00002916292,0.00001741037,0.0001415668,0.000020597,0.00002586125],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008505313,"threshold_uncertainty_score":0.9690728,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008814553048158688,"score_gpt":0.2486277847795551,"score_spread":0.2398132317313964,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}