{"id":"W2052309165","doi":"10.1016/j.neulet.2007.02.073","title":"VX-induced cell death involves activation of caspase-3 in cultured rat cortical neurons","year":2007,"lang":"en","type":"article","venue":"Neuroscience Letters","topic":"Pesticide Exposure and Toxicity","field":"Agricultural and Biological Sciences","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"Defence Research and Development Canada","funders":"","keywords":"Programmed cell death; Propidium iodide; Caspase; Apoptosis; Poly ADP ribose polymerase; Cell biology; Biology; Caspase 3; Proteases; Molecular biology; Biochemistry; Enzyme; Polymerase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002659979,0.0001186601,0.0001380892,0.00003092829,0.0001207167,0.000031548,0.0002677754,0.0000605112,0.0000158543],"category_scores_gemma":[0.0002103184,0.00005243937,0.00005200044,0.0006258499,0.0001056613,0.0002184586,0.0000475484,0.0002143989,0.000003357818],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002121492,"about_ca_system_score_gemma":0.000007944557,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002396986,"about_ca_topic_score_gemma":0.0002571242,"domain_scores_codex":[0.9986889,0.00007612096,0.0002551842,0.0003284107,0.0002918675,0.0003594536],"domain_scores_gemma":[0.9994756,0.0002393697,0.00009455125,0.00006489798,0.00002270873,0.000102892],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00001589116,0.00008560575,0.04176652,0.000002031898,1.795546e-7,0.00002333429,0.00005645615,0.00001973567,0.9572008,0.00006104325,0.0001034727,0.0006648951],"study_design_scores_gemma":[0.0000732973,0.0001269263,0.5045013,0.000005052053,0.000001833689,0.000003035955,0.00003397897,0.00006507359,0.4949237,0.00002048907,0.0001696626,0.00007571402],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971986,0.000002545523,0.00007702259,0.002049675,0.0002411496,0.0001364945,0.000003275573,0.00003013457,0.0002611419],"genre_scores_gemma":[0.9941826,0.000002331941,0.00007756038,0.005630414,0.00008270454,0.000002689642,0.000003641281,8.313862e-7,0.00001715442],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4627348,"threshold_uncertainty_score":0.2138416,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03882824185373678,"score_gpt":0.2461571678366042,"score_spread":0.2073289259828674,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}