{"id":"W2052326314","doi":"10.1006/geno.2000.6481","title":"Synergy between tetA and rpsL Provides High-Stringency Positive and Negative Selection in Bacterial Artificial Chromosome Vectors","year":2001,"lang":"en","type":"article","venue":"Genomics","topic":"Bacteriophages and microbial interactions","field":"Environmental Science","cited_by":26,"is_retracted":false,"has_abstract":false,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"Medical Research Council Canada; Cancer Research Society","keywords":"Biology; Selectable marker; Kanamycin; Genetics; Context (archaeology); Streptomycin; Auxotrophy; Escherichia coli; Molecular biology; Gene; Plasmid; Antibiotics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008793481,0.0007873898,0.000717325,0.0007456338,0.0003050501,0.0008997709,0.001063289,0.0006513579,0.002857058],"category_scores_gemma":[0.0005879177,0.0007965245,0.000582313,0.0005101847,0.0005819014,0.0005757131,0.00101917,0.001913889,0.002829586],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005532493,"about_ca_system_score_gemma":0.0003457699,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003685679,"about_ca_topic_score_gemma":0.001233095,"domain_scores_codex":[0.9987525,0.0003579478,0.0001712748,0.000199591,0.0003883278,0.0001303195],"domain_scores_gemma":[0.9990959,0.0003052609,0.000171294,0.0001600575,0.00006392237,0.0002035581],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001326564,0.00004175344,0.00007137244,0.0000301306,0.000005151101,0.00002320275,0.0000167742,0.00004638154,0.9971527,0.0003444979,0.000141168,0.001994248],"study_design_scores_gemma":[0.00002617374,0.00007216697,0.0004012667,0.000004370647,0.00001200694,0.0001156695,0.00000827555,0.0006840086,0.995723,0.00005379535,0.002890101,0.000009182328],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7991992,0.001186976,0.1835989,0.0008415812,0.0003436827,0.0006594316,0.00235952,0.00435754,0.007453103],"genre_scores_gemma":[0.8982239,0.0006523444,0.07320783,0.0002871831,0.00007149643,0.0005441665,0.003858517,0.001690785,0.02146369],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002857058,"threshold_uncertainty_score":0.009557843,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00882183475706679,"score_gpt":0.2128642999669343,"score_spread":0.2040424652098675,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}