{"id":"W2052340069","doi":"10.1016/s0006-291x(02)00413-8","title":"Cytotoxic activity of 2′,2′-difluorodeoxycytidine, 5-aza-2′-deoxycytidine and cytosine arabinoside in cells transduced with deoxycytidine kinase gene","year":2002,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Biochemical and Molecular Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"Sveriges Lantbruksuniversitet","keywords":"Deoxycytidine kinase; Deoxycytidine; Cytidine deaminase; Cytotoxic T cell; Cell culture; Cytidine; Biology; Molecular biology; Biochemistry; Chemistry; Cancer research; Enzyme; In vitro; Gemcitabine; Cancer; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000473194,0.0003021435,0.0004096268,0.0001867588,0.0001925105,0.00004498327,0.0007350859,0.000286824,0.00001761413],"category_scores_gemma":[0.0002626266,0.0002468517,0.0001009267,0.0007619482,0.001641782,0.00001814656,0.0007553914,0.0007328489,0.000006365305],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004089799,"about_ca_system_score_gemma":0.00007436868,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001726754,"about_ca_topic_score_gemma":0.00004114827,"domain_scores_codex":[0.9973868,0.0003356584,0.0003538647,0.0007251545,0.0005406491,0.000657843],"domain_scores_gemma":[0.9977265,0.0002159583,0.00007168567,0.001285317,0.0002888412,0.0004117142],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000402321,0.001079816,0.0001948976,0.0001026809,0.00004707128,0.000006794245,0.00003909612,7.684683e-7,0.9952359,0.0002860207,0.0003696773,0.002235],"study_design_scores_gemma":[0.001272071,0.0007689811,0.001973873,0.00008287271,0.00001915172,0.00001783938,0.00002492606,0.0009311759,0.9936639,0.0001131232,0.0008377287,0.0002943637],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935637,0.002976222,0.0001332796,0.002390527,0.000007622838,0.0005443666,0.00007916051,0.00001587972,0.0002893137],"genre_scores_gemma":[0.991713,0.005867605,0.001885676,0.00005552436,0.00007366334,0.00012927,0.00008807509,0.00003599112,0.000151134],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002891383,"threshold_uncertainty_score":0.9999984,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05440478576465901,"score_gpt":0.3160839490997522,"score_spread":0.2616791633350932,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}