{"id":"W2052340508","doi":"10.1371/journal.pone.0002144","title":"Concordant Gene Expression in Leukemia Cells and Normal Leukocytes Is Associated with Germline cis-SNPs","year":2008,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Genomics and Rare Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Cancer Institute; National Institutes of Health; National Institute of General Medical Sciences; American Lebanese Syrian Associated Charities; McGill University","keywords":"Biology; Single-nucleotide polymorphism; Gene; Gene expression; Genetics; International HapMap Project; Housekeeping gene; Germline; Gene expression profiling; SNP genotyping; Genotype; Molecular biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005316156,0.0001591621,0.0004556235,0.0005770161,0.0002407438,0.0004674212,0.0001464532,0.0002304485,0.0006914496],"category_scores_gemma":[0.001656682,0.0001956238,0.0001933525,0.0006266414,0.0005258472,0.0001151071,0.0003106623,0.0002577289,0.0001318634],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002419554,"about_ca_system_score_gemma":0.0001358468,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006766417,"about_ca_topic_score_gemma":0.001243151,"domain_scores_codex":[0.999011,0.0002162443,0.00007435497,0.0004118268,0.000163446,0.0001232085],"domain_scores_gemma":[0.9988437,0.0005057359,0.0003482183,0.000142685,0.00007177021,0.00008792111],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001307289,0.00002920567,0.6543361,0.00009000011,0.000230008,0.0004756434,0.0003921036,0.0004310571,0.3367208,0.0001957884,0.00009882882,0.005693159],"study_design_scores_gemma":[0.0000185612,0.0001596397,0.971153,0.000005918276,0.00009158276,0.001230583,0.0001190912,0.0005053659,0.02611018,0.0002520793,0.0003461892,0.000007790445],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992847,0.0001442651,0.0003135012,0.00001028815,0.000001660531,0.000001885115,0.0001128401,0.000005623884,0.0001253472],"genre_scores_gemma":[0.9993425,0.00004032059,0.000315187,0.00001606593,0.000002353882,0.000005177649,0.0002039448,0.000003936443,0.00007041418],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006914496,"threshold_uncertainty_score":0.002811491,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01619572900871531,"score_gpt":0.1909272806421278,"score_spread":0.1747315516334125,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}