{"id":"W2052344090","doi":"10.1182/blood.v98.9.2664","title":"High-level erythroid-specific gene expression in primary human and murine hematopoietic cells with self-inactivating lentiviral vectors","year":2001,"lang":"en","type":"article","venue":"Blood","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":115,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Biology; Molecular biology; Viral vector; Haematopoiesis; Woodchuck hepatitis virus; Enhancer; Myeloid; Transplantation; Genetic enhancement; Virology; Stem cell; Gene expression; Gene; Virus; Cancer research; Cell biology; Genetics; Hepatitis B virus; Recombinant DNA; Medicine; Hepadnaviridae","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001847053,0.0002028106,0.0001970136,0.00008715007,0.0001168088,0.00003307863,0.000158033,0.0001138454,0.00002523608],"category_scores_gemma":[0.000004280061,0.0001799587,0.00003433835,0.0001492011,0.00007018035,0.000009064769,0.0001368847,0.0001585023,0.00000416464],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002973151,"about_ca_system_score_gemma":0.00004914678,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001701412,"about_ca_topic_score_gemma":0.00006428768,"domain_scores_codex":[0.9986662,0.00009327789,0.0001983134,0.0004688679,0.0002127004,0.0003606536],"domain_scores_gemma":[0.9994242,0.00001348536,0.00007105697,0.0003694243,0.00003976861,0.00008212082],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000406035,0.0005144597,0.01117056,0.00003446001,0.00003723659,0.00004981316,0.00009565784,0.00002008504,0.9873086,0.000002983925,0.00005750839,0.0003025648],"study_design_scores_gemma":[0.00322458,0.001418833,0.009886863,0.00004397086,0.000009949806,0.00004458108,0.00004321597,0.000001742581,0.9848509,0.00001876897,0.0002252062,0.0002313806],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984414,0.0008887373,0.00009449705,0.00002868387,0.00002552584,0.0002585168,0.000007657824,0.00002413695,0.0002308353],"genre_scores_gemma":[0.9963259,0.0003962603,0.002744704,0.00004198146,0.0001608574,0.00003351828,0.00006302557,0.00004687114,0.0001869112],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002818545,"threshold_uncertainty_score":0.7338504,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01454357503932512,"score_gpt":0.2422471103933828,"score_spread":0.2277035353540577,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}