{"id":"W2052344303","doi":"10.1007/s11427-014-4693-3","title":"ACE2/Ang-(1–7) signaling and vascular remodeling","year":2014,"lang":"en","type":"review","venue":"Science China Life Sciences","topic":"Renin-Angiotensin System Studies","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Key Research and Development Program of China; Major Research Plan; National Natural Science Foundation of China","keywords":"Angiotensin II; Vascular smooth muscle; Fibrosis; Angiotensin-converting enzyme 2; Signal transduction; Renin–angiotensin system; Inflammation; Regulator; Vascular remodelling in the embryo; Oxidative stress; Vascular tone; Medicine; Biology; Cell biology; Internal medicine; Receptor; Blood pressure; Biochemistry; Vasodilation; Smooth muscle; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002995298,0.0005756406,0.0008234733,0.001543838,0.0002334562,0.0006883971,0.0004451647,0.0006806841,0.002544817],"category_scores_gemma":[0.0004265145,0.0001708461,0.0003329317,0.001571113,0.0002833329,0.0008866392,0.0004448487,0.0009393204,0.001206753],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004022823,"about_ca_system_score_gemma":0.0008951093,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005962396,"about_ca_topic_score_gemma":0.001370547,"domain_scores_codex":[0.9998865,0.00001817481,0.00001947364,0.00001954564,0.00004574357,0.00001056513],"domain_scores_gemma":[0.9998716,0.00004784427,0.00002349061,0.000003410901,0.00003879387,0.00001486911],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008110284,0.00007391586,0.0003174057,0.01971743,0.0001014302,0.0003573458,0.00008260959,0.0002717923,0.00299998,0.003525177,0.02016832,0.9523036],"study_design_scores_gemma":[0.00002042395,0.000106492,0.002049552,0.00362184,0.0001498023,0.002797313,0.0001088492,0.0001042484,0.001004252,0.002294365,0.9877252,0.00001763717],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000160391,0.9987755,0.00007100007,0.0001674958,0.00011355,0.000002837791,0.000009317706,0.000003857956,0.0006960295],"genre_scores_gemma":[0.0008401722,0.9984837,0.0001014044,0.00008268456,0.00009032615,0.00000345081,0.00001074484,4.807417e-7,0.000386975],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002544817,"threshold_uncertainty_score":0.008513272,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07962637847353005,"score_gpt":0.3835984555237361,"score_spread":0.303972077050206,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}