{"id":"W2052344303","doi":"10.1007/s11427-014-4693-3","title":"ACE2/Ang-(1–7) signaling and vascular remodeling","year":2014,"lang":"en","type":"review","venue":"Science China Life Sciences","topic":"Renin-Angiotensin System Studies","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Key Research and Development Program of China; Major Research Plan; National Natural Science Foundation of China","keywords":"Angiotensin II; Vascular smooth muscle; Fibrosis; Angiotensin-converting enzyme 2; Signal transduction; Renin–angiotensin system; Inflammation; Regulator; Vascular remodelling in the embryo; Oxidative stress; Vascular tone; Medicine; Biology; Cell biology; Internal medicine; Receptor; Blood pressure; Biochemistry; Vasodilation; Smooth muscle; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts"],"consensus_categories":["sts"],"category_scores_codex":[0.008331999,0.0006118807,0.002650933,0.0009964525,0.001759462,0.0003375421,0.001087201,0.0002037355,0.00001471574],"category_scores_gemma":[0.002861781,0.0003786013,0.0005030099,0.00334727,0.004930744,0.0004559163,0.0006012452,0.0004437997,0.00007423083],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001437896,"about_ca_system_score_gemma":0.0021978,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004996153,"about_ca_topic_score_gemma":0.000002071218,"domain_scores_codex":[0.9939057,0.000193556,0.0009531043,0.001763203,0.002205396,0.0009790809],"domain_scores_gemma":[0.9975266,0.0002713432,0.0005837545,0.0007627946,0.0002581975,0.0005973245],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00000496662,0.00005951758,0.001082822,0.009973166,0.0002168546,0.00002223133,0.001703491,0.00009994313,0.000174072,0.001033121,0.0009055915,0.9847242],"study_design_scores_gemma":[0.0004461338,0.0005483556,0.001128296,0.05467243,0.001726624,0.0005747619,0.0003822043,0.00321246,0.00001996626,0.0003334643,0.9354551,0.001500215],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001619615,0.9930392,0.0002290438,0.0003223012,0.0008608932,0.0009066728,0.000003241035,0.0001184085,0.002900651],"genre_scores_gemma":[0.004110679,0.9894871,0.005376669,0.0001566698,0.000630682,0.00002508625,0.000002313481,0.00003448873,0.0001762988],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.983224,"threshold_uncertainty_score":0.9998666,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07962637847353005,"score_gpt":0.3835984555237361,"score_spread":0.303972077050206,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}