{"id":"W2052350491","doi":"10.1172/jci28310","title":"Hematopoietic stem cells proliferate until after birth and show a reversible phase-specific engraftment defect","year":2006,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":377,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; Terry Fox Foundation; National Cancer Institute; National Institutes of Health; Michael Smith Health Research BC; Stem Cell Network","keywords":"Haematopoiesis; Stromal cell; Stem cell; CXC chemokine receptors; Cell biology; Biology; Cell cycle; Stem cell factor; Chemokine; Hematopoietic stem cell; Stromal cell-derived factor 1; Immunology; Cancer research; CXCR4; Cell; Chemokine receptor; Immune system; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001075392,0.0003861041,0.0002159795,0.0002799029,0.0001234566,0.0001915204,0.00017238,0.000203597,0.002504492],"category_scores_gemma":[0.0001291381,0.0001394958,0.0001415421,0.000130293,0.0002616869,0.0001482107,0.0002334219,0.0004052144,0.0009392062],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001508643,"about_ca_system_score_gemma":0.0001606584,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002838782,"about_ca_topic_score_gemma":0.0003908596,"domain_scores_codex":[0.9999163,0.000009640777,0.000009869053,0.00001473934,0.00003216907,0.00001718874],"domain_scores_gemma":[0.9997782,0.00003663474,0.00007155974,0.00002776643,0.00002587479,0.0000600499],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001257372,0.00002674077,0.001886675,0.00004837064,0.000006661625,0.0001323616,0.00003963019,0.0000501115,0.9872328,0.000250265,0.0001065359,0.01009414],"study_design_scores_gemma":[0.0000182602,0.0007532476,0.0308488,0.00001678372,0.00002247776,0.001949651,0.00005390885,0.0003407239,0.9584996,0.0002074847,0.007283171,0.000005797179],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.98482,0.006002592,0.004398112,0.00014385,0.0000232997,0.00003741496,0.0007689526,0.0003728093,0.003433046],"genre_scores_gemma":[0.9890357,0.002112333,0.001722066,0.00005423955,0.00001416692,0.00003528893,0.001230394,0.00003633202,0.005759513],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002504492,"threshold_uncertainty_score":0.008378386,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05487808557512715,"score_gpt":0.3283187011934843,"score_spread":0.2734406156183572,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}