{"id":"W2052370726","doi":"10.1158/0008-5472.can-06-2027","title":"A Src/Abl Kinase Inhibitor, SKI-606, Blocks Breast Cancer Invasion, Growth, and Metastasis <i>In vitro</i> and <i>In vivo</i>","year":2007,"lang":"en","type":"article","venue":"Cancer Research","topic":"Chronic Myeloid Leukemia Treatments","field":"Medicine","cited_by":147,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"","keywords":"Metastasis; Cancer research; Protein kinase B; Proto-oncogene tyrosine-protein kinase Src; Cancer; Angiogenesis; Breast cancer; Biology; Tyrosine kinase; In vivo; Kinase; Medicine; Pathology; Internal medicine; Receptor; Signal transduction; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000157681,0.0005155769,0.0005372346,0.0003007092,0.0001333448,0.0002542439,0.000225455,0.0002036729,0.0009611983],"category_scores_gemma":[0.00007464444,0.0001706941,0.0004022645,0.0002337232,0.0002272617,0.0001894484,0.0001073548,0.0007796471,0.0004496514],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002564068,"about_ca_system_score_gemma":0.0003191506,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009071421,"about_ca_topic_score_gemma":0.002138614,"domain_scores_codex":[0.9998509,0.00002286793,0.00001459626,0.00001663017,0.00004262605,0.00005241239],"domain_scores_gemma":[0.9999257,0.00001256497,0.00002416739,0.000006634171,0.000008883701,0.00002189288],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000222989,0.0001789897,0.0001787766,0.0001298741,0.00001148625,0.00003697043,0.000008507961,0.00009137068,0.995787,0.00004447929,0.0001501551,0.003159425],"study_design_scores_gemma":[0.00007679305,0.001793829,0.003745987,0.000007202761,0.00003819939,0.0003200485,0.0000146361,0.0007631201,0.9914984,0.00001984252,0.001717255,0.000004675502],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9831065,0.01085298,0.00194919,0.0002529686,0.00007923791,0.00005319112,0.0005911227,0.0001820209,0.002932814],"genre_scores_gemma":[0.9818556,0.01113294,0.002743719,0.00009037946,0.00003505978,0.0000616953,0.001727613,0.00003317178,0.002319878],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009611983,"threshold_uncertainty_score":0.003215492,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03518316479279709,"score_gpt":0.3539265792039707,"score_spread":0.3187434144111737,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}