{"id":"W2052372808","doi":"10.1182/blood-2007-07-103291","title":"Loss of TLE1 and TLE4 from the del(9q) commonly deleted region in AML cooperates with AML1-ETO to affect myeloid cell proliferation and survival","year":2008,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":89,"is_retracted":false,"has_abstract":true,"ca_institutions":"Pediatric Oncology Group","funders":"National Cancer Institute; National Heart, Lung, and Blood Institute","keywords":"Myeloid leukemia; Biology; Myeloid; Cancer research; Gene knockdown; Haematopoiesis; Fusion gene; Haploinsufficiency; Cell growth; Leukemia; Progenitor cell; Stem cell; Cell culture; Gene; Genetics; Phenotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001373883,0.0003830339,0.0003655654,0.0003328888,0.0001814425,0.0002576608,0.0002098345,0.000300376,0.0009433617],"category_scores_gemma":[0.0001268221,0.0001838629,0.0002758826,0.0001475239,0.0002547843,0.0001570327,0.0003372049,0.0005458952,0.0003342929],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004747366,"about_ca_system_score_gemma":0.000254393,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008908767,"about_ca_topic_score_gemma":0.0017513,"domain_scores_codex":[0.9998254,0.00002052047,0.00002658402,0.000033877,0.00005327735,0.0000403756],"domain_scores_gemma":[0.9998869,0.00002268959,0.00003570476,0.00001359312,0.000006817006,0.00003433107],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000366752,0.00002137695,0.00019132,0.00001016157,0.000003755339,0.00004472155,0.000007086031,0.0001087392,0.9989406,0.00006487533,0.00002152233,0.0005491024],"study_design_scores_gemma":[0.00002122598,0.0002011419,0.003607457,0.000002592389,0.00001516453,0.0002379403,0.00001530871,0.001244277,0.9929003,0.00002498941,0.001725695,0.000004049485],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964911,0.0004328677,0.001724483,0.00007398867,0.0000142924,0.00003470268,0.0003358465,0.00009728096,0.0007954764],"genre_scores_gemma":[0.9940566,0.0003146978,0.001848201,0.00004336519,0.000004300895,0.00004711442,0.0006696929,0.00002176185,0.002994272],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009433617,"threshold_uncertainty_score":0.003444493,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01928967759538882,"score_gpt":0.2499486258918426,"score_spread":0.2306589482964538,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}