{"id":"W2052372808","doi":"10.1182/blood-2007-07-103291","title":"Loss of TLE1 and TLE4 from the del(9q) commonly deleted region in AML cooperates with AML1-ETO to affect myeloid cell proliferation and survival","year":2008,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":89,"is_retracted":false,"has_abstract":true,"ca_institutions":"Pediatric Oncology Group","funders":"National Cancer Institute; National Heart, Lung, and Blood Institute","keywords":"Myeloid leukemia; Biology; Myeloid; Cancer research; Gene knockdown; Haematopoiesis; Fusion gene; Haploinsufficiency; Cell growth; Leukemia; Progenitor cell; Stem cell; Cell culture; Gene; Genetics; Phenotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002461132,0.0001591359,0.0003304768,0.00009393556,0.00009385421,0.00001877609,0.00009750068,0.00009216778,0.000006395109],"category_scores_gemma":[0.000125527,0.0001015141,0.0000181014,0.0003537537,0.00019699,0.00009012715,0.00007777277,0.0002675543,0.00000473853],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005398322,"about_ca_system_score_gemma":0.0002105098,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001939964,"about_ca_topic_score_gemma":0.001730159,"domain_scores_codex":[0.9988012,0.0001724594,0.0002093549,0.0002918607,0.0002885655,0.0002365687],"domain_scores_gemma":[0.9990599,0.0003011792,0.00005314732,0.0002995187,0.0001538695,0.0001324021],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001229065,0.0003320945,0.9677955,0.00007888214,0.00007677155,0.0003138054,0.001608028,0.00001796115,0.02728649,0.0000372271,0.000796312,0.0004278678],"study_design_scores_gemma":[0.01337386,0.00195066,0.846838,0.0002578703,0.0001486222,0.0004959736,0.0006005394,0.0007142919,0.1349466,0.00001582529,0.0004032624,0.0002544496],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964004,0.0006073346,0.00009931177,0.001675428,0.00001153413,0.0009120755,0.00001694584,0.00002269982,0.000254272],"genre_scores_gemma":[0.998486,0.0003284335,0.0005019402,0.000344556,0.00008885273,0.00003469191,0.00004296144,0.00002717413,0.0001454287],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1209575,"threshold_uncertainty_score":0.4139627,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01928967759538882,"score_gpt":0.2499486258918426,"score_spread":0.2306589482964538,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}