{"id":"W2052373965","doi":"10.1038/ni.2241","title":"A new path to IL-1β production controlled by caspase-8","year":2012,"lang":"en","type":"letter","venue":"Nature Immunology","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Inflammasome; Proinflammatory cytokine; Caspase 1; Cytokine; Biology; Stimulation; Immunology; Cell biology; Microbiology; Inflammation; Neuroscience","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009677965,0.0007027415,0.0007970497,0.0002869219,0.000749324,0.001780364,0.0006064542,0.006235024,0.003934419],"category_scores_gemma":[0.002330462,0.0003015947,0.0005809861,0.000182168,0.001597332,0.002447844,0.0009252963,0.01117865,0.001981253],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001109477,"about_ca_system_score_gemma":0.0005327082,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001093297,"about_ca_topic_score_gemma":0.0002054274,"domain_scores_codex":[0.999525,0.000116407,0.000049951,0.00007151644,0.0001558804,0.00008132886],"domain_scores_gemma":[0.9992625,0.0003682788,0.00008076483,0.00007902757,0.0001033733,0.0001059722],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003533841,0.000439622,0.001472401,0.001019148,0.0001128454,0.01576246,0.0003174835,0.0005393347,0.05951117,0.08140536,0.6917236,0.1441628],"study_design_scores_gemma":[0.001664406,0.0007339008,0.001998026,0.0002771754,0.00007672112,0.01207188,0.0002899303,0.002196593,0.02749522,0.09300558,0.8601107,0.00007987684],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.01481302,0.0531372,0.005851612,0.8479148,0.06462377,0.00006372688,0.0001941633,0.0003388438,0.01306299],"genre_scores_gemma":[0.2743025,0.06158909,0.01047453,0.4359563,0.1770529,0.0005003763,0.0002539761,0.0001118908,0.03975829],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.006235024,"threshold_uncertainty_score":0.0131619,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002651905791620384,"score_gpt":0.2135446426946936,"score_spread":0.2108927369030732,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}