{"id":"W2052410544","doi":"10.1038/cdd.2013.127","title":"PTEN, here, there, everywhere","year":2013,"lang":"en","type":"editorial","venue":"Cell Death and Differentiation","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network; Ontario Institute for Cancer Research; University of Toronto","funders":"","keywords":"PTEN; Computational biology; Cancer research; Biology; Cell biology; Signal transduction; PI3K/AKT/mTOR pathway","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0000786572,0.0003584378,0.0002695012,0.00004782379,0.00009288522,0.0001240273,0.0002060237,0.001071516,0.0001139312],"category_scores_gemma":[0.00006302077,0.0003272907,0.0001135132,0.00003640263,0.00003673134,0.000006142635,0.0001124059,0.0002739878,0.00004268876],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003584318,"about_ca_system_score_gemma":0.0001281041,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001692123,"about_ca_topic_score_gemma":0.0000341542,"domain_scores_codex":[0.9984781,0.00006668024,0.0002642864,0.0005880794,0.0003087161,0.0002941014],"domain_scores_gemma":[0.9990205,0.00004545215,0.000233007,0.0003952744,0.0002021746,0.0001035845],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003716299,0.00005088356,0.001268085,0.0001678376,0.0000535461,0.000001176158,0.000007507211,0.000004871139,0.03301089,0.000007956344,0.9643428,0.001047281],"study_design_scores_gemma":[0.001073986,0.000226365,0.00219568,0.00007552149,0.000152355,8.496757e-7,0.00001140326,0.0001188481,0.02798991,0.0002971132,0.9672254,0.0006325908],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"editorial","genre_gemma":"editorial","genre_scores_codex":[0.3015777,0.01939767,0.002518537,0.00002027411,0.6653614,0.0006503839,0.0003531695,0.00006900018,0.01005189],"genre_scores_gemma":[0.3539802,0.002466629,0.0001849194,0.00005709611,0.610411,0.0001249225,0.008419047,0.0001306446,0.0242255],"genre_candidate":"editorial","genre_consensus":"editorial","teacher_disagreement_score":0.05495032,"threshold_uncertainty_score":0.9999179,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006757098503282463,"score_gpt":0.2270219864001745,"score_spread":0.220264887896892,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}