{"id":"W2052473382","doi":"10.1074/jbc.m306936200","title":"hSef Inhibits PC-12 Cell Differentiation by Interfering with Ras-Mitogen-activated Protein Kinase MAPK Signaling","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":82,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of Toronto; Tsinghua University; Washington University in St. Louis","keywords":"MAPK/ERK pathway; Cell biology; Protein kinase A; Mitogen-activated protein kinase; Kinase; Chemistry; Mitogen-activated protein kinase kinase; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001457683,0.0004589812,0.0002952525,0.0002387772,0.0001333979,0.0002116647,0.0002150435,0.000237854,0.001079036],"category_scores_gemma":[0.0001226714,0.0001164499,0.0002211318,0.0001666583,0.0002089068,0.000122994,0.0001576675,0.000435805,0.0003628806],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002513981,"about_ca_system_score_gemma":0.000245271,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008870905,"about_ca_topic_score_gemma":0.001333181,"domain_scores_codex":[0.9998393,0.00002962681,0.00001635249,0.00001816679,0.00004676223,0.00004977396],"domain_scores_gemma":[0.9999049,0.00003074173,0.00001473286,0.00001423899,0.000009381289,0.00002590261],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008646592,0.00005363627,0.0001168763,0.00002245971,0.000005298205,0.00003874474,0.000009858802,0.00007641871,0.9979855,0.0001018351,0.00005281253,0.001450017],"study_design_scores_gemma":[0.00001975288,0.0002332283,0.001763158,0.000003816197,0.000009442098,0.000111588,0.000009187449,0.00105183,0.9949633,0.00002831988,0.001804169,0.000002064551],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994361,0.001215937,0.002178432,0.00009421218,0.0000220439,0.00002842142,0.0003053945,0.0001079041,0.001686709],"genre_scores_gemma":[0.9919888,0.001060822,0.002191591,0.00004273413,0.0000110759,0.00004347727,0.0009466534,0.00002336515,0.003691387],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001079036,"threshold_uncertainty_score":0.003609717,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01201393225071313,"score_gpt":0.2123391484981892,"score_spread":0.2003252162474761,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}