{"id":"W2052481750","doi":"10.1128/aem.68.1.194-200.2002","title":"Mutagenic Analysis of a Conserved Region of Domain III in the Cry1Ac Toxin of <i>Bacillus thuringiensis</i>","year":2002,"lang":"en","type":"article","venue":"Applied and Environmental Microbiology","topic":"Insect Resistance and Genetics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Biotechnology Research Institute","funders":"","keywords":"Bacillus thuringiensis; Cry1Ac; Mutant; Toxin; Biology; Biochemistry; Amino acid; Aspartic acid; Mutagenesis; Arginine; Threonine; Bacillaceae; Bioassay; Site-directed mutagenesis; Bacillus subtilis; Serine; Bacteria; Genetics; Gene; Transgene; Genetically modified crops","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001802341,0.0005847845,0.0002688404,0.0001856961,0.0001595784,0.0001919099,0.0003007585,0.0003619244,0.0008216007],"category_scores_gemma":[0.0001919943,0.0001542026,0.000532501,0.0001543908,0.0002860992,0.00007866928,0.0002095845,0.0005453954,0.0004423479],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004335699,"about_ca_system_score_gemma":0.0002495052,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002080465,"about_ca_topic_score_gemma":0.002353798,"domain_scores_codex":[0.9998228,0.00004064201,0.00002631308,0.00004067485,0.00004658284,0.00002296508],"domain_scores_gemma":[0.999743,0.0000544456,0.0001188942,0.00002386662,0.00002394989,0.00003577819],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006637078,0.00002335622,0.0002549516,0.00002922969,0.00001080688,0.000117584,0.00001322391,0.0001339555,0.9986287,0.00005212137,0.000022294,0.0006472585],"study_design_scores_gemma":[0.00005778215,0.000442192,0.009941562,0.00002362033,0.00007897176,0.001056225,0.00004538168,0.001448231,0.9847045,0.00003947554,0.002146292,0.00001573045],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927245,0.0002625083,0.005208395,0.0000912039,0.00004045092,0.00009857713,0.0004680895,0.00009456367,0.001011749],"genre_scores_gemma":[0.9937041,0.0001872081,0.004570561,0.00007740945,0.000008128862,0.00003492576,0.000642176,0.00005278941,0.0007225893],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002080465,"threshold_uncertainty_score":0.004136682,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005640659855484564,"score_gpt":0.1694069579905937,"score_spread":0.1637662981351092,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}