{"id":"W2052483400","doi":"10.1016/j.stem.2013.02.001","title":"Opposing Regulation of Sox2 by Cell-Cycle Effectors E2f3a and E2f3b in Neural Stem Cells","year":2013,"lang":"en","type":"article","venue":"Cell stem cell","topic":"Congenital heart defects research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":89,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Biology; SOX2; Neural stem cell; Effector; Cell biology; Stem cell; Cell cycle; Cell; Neuroscience; Genetics; Gene; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002261,0.000211138,0.000281419,0.000289501,0.0002638353,0.0008620532,0.0001936977,0.0002542294,0.001530411],"category_scores_gemma":[0.0002020711,0.0001932592,0.0002326808,0.0001664828,0.0003479321,0.0004860392,0.0003650173,0.0003980408,0.0003176447],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005154727,"about_ca_system_score_gemma":0.0003116018,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009039324,"about_ca_topic_score_gemma":0.002051799,"domain_scores_codex":[0.999822,0.00002618219,0.00001425126,0.00003136588,0.00005156005,0.00005462138],"domain_scores_gemma":[0.9998807,0.00002980692,0.00001790099,0.00001450265,0.00002173892,0.00003537352],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003682771,0.00002154215,0.001072933,0.00001876783,0.000006059998,0.00007072147,0.0000282804,0.0001303213,0.9947928,0.001240483,0.00006034827,0.00218946],"study_design_scores_gemma":[0.00003028259,0.00006342054,0.01376948,0.000004375904,0.000008988153,0.0001497689,0.00009278312,0.001315842,0.9821587,0.0004178633,0.001984097,0.000004202018],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939669,0.002019838,0.001507922,0.0001241112,0.00002943671,0.000005850642,0.0001778067,0.00003541374,0.002132674],"genre_scores_gemma":[0.996786,0.0004210104,0.0005221734,0.00003938304,0.000005112041,0.000007431324,0.0001846917,0.0000162615,0.002017868],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001530411,"threshold_uncertainty_score":0.005119741,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006344733769204729,"score_gpt":0.2166595052253522,"score_spread":0.2103147714561475,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}