{"id":"W2052483400","doi":"10.1016/j.stem.2013.02.001","title":"Opposing Regulation of Sox2 by Cell-Cycle Effectors E2f3a and E2f3b in Neural Stem Cells","year":2013,"lang":"en","type":"article","venue":"Cell stem cell","topic":"Congenital heart defects research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":89,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Biology; SOX2; Neural stem cell; Effector; Cell biology; Stem cell; Cell cycle; Cell; Neuroscience; Genetics; Gene; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002007942,0.0001960659,0.0002182069,0.00007889469,0.00005942405,0.00004868549,0.0001587022,0.0001908104,0.00005463555],"category_scores_gemma":[0.000002519194,0.0001953815,0.0000732285,0.0001357439,0.00007925808,0.00001421548,0.0002045178,0.0001404671,0.00004290046],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002727638,"about_ca_system_score_gemma":0.00003492731,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001953253,"about_ca_topic_score_gemma":0.00002516764,"domain_scores_codex":[0.9985025,0.0001808936,0.0002921446,0.0004220605,0.0001926396,0.0004097983],"domain_scores_gemma":[0.9992642,0.00007791023,0.00009059045,0.0003479087,0.00007121296,0.0001482134],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002990689,0.00008713834,0.002515654,0.0003105029,0.0000044093,0.000001987929,0.00007959155,0.00007952945,0.9884829,3.830952e-7,0.001179768,0.007228266],"study_design_scores_gemma":[0.0006232895,0.0003110835,0.002544869,0.00001975498,0.000009094011,0.000002280372,0.0001304255,0.002725819,0.9925354,0.000003293474,0.0008963362,0.0001984174],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992542,0.003823552,0.00004070261,0.00001423605,0.00009683072,0.000644439,0.00001321885,0.00001001119,0.002814963],"genre_scores_gemma":[0.9943079,0.00009866038,0.00005009011,0.00001995881,0.00003829351,0.00002525079,0.00002235713,0.00003751483,0.005399934],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007029848,"threshold_uncertainty_score":0.7967426,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006344733769204729,"score_gpt":0.2166595052253522,"score_spread":0.2103147714561475,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}