{"id":"W2052487518","doi":"10.1159/000058383","title":"Ectopic ACTH Syndrome: Discrepancy between Somatostatin Receptor Status in vivo and ex vivo, and between Immunostaining and Gene Transcription for POMC and CRH","year":2002,"lang":"en","type":"article","venue":"Hormone Research in Paediatrics","topic":"Pituitary Gland Disorders and Treatments","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Endocrinology; Internal medicine; Somatostatin receptor; Ex vivo; Somatostatin; Proopiomelanocortin; In vivo; Corticotropin-releasing hormone; Immunostaining; Biology; Receptor; Medicine; Immunohistochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006810526,0.0002133071,0.0004805326,0.0006103987,0.000167205,0.00005887666,0.00004946775,0.0001628139,0.00001215465],"category_scores_gemma":[0.0001938679,0.0001877096,0.00003029585,0.0004929636,0.0001505415,0.0002381779,0.00007796996,0.0003364875,0.000001210485],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001132695,"about_ca_system_score_gemma":0.00006232385,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006643748,"about_ca_topic_score_gemma":0.00005802875,"domain_scores_codex":[0.9979289,0.0001401176,0.0003797374,0.0004693662,0.0003633639,0.000718532],"domain_scores_gemma":[0.9987384,0.0006383705,0.00005277435,0.0001662313,0.00005917716,0.0003450282],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001821742,0.0001160457,0.9715738,0.0002452309,0.0000560696,0.00008413496,0.001622129,1.525757e-7,0.0007593062,0.00002672407,0.0002197712,0.02511442],"study_design_scores_gemma":[0.0107117,0.00193891,0.9829254,0.00007882465,0.00009095103,0.00003531203,0.001112145,0.0002401402,0.0001762555,0.001684318,0.0007679835,0.0002381291],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9518554,0.04600077,0.00004780993,0.0005564839,0.00001758592,0.001076275,0.0002975309,0.0000185146,0.0001296667],"genre_scores_gemma":[0.9506902,0.04754386,0.001381339,0.00001173267,0.0000741046,0.00007209123,0.0000923953,0.0000292114,0.0001051409],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02487629,"threshold_uncertainty_score":0.7654574,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06636204020975872,"score_gpt":0.3313111182305975,"score_spread":0.2649490780208388,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}