{"id":"W2052552085","doi":"10.1369/jhc.6a7087.2006","title":"Osteopontin Upregulation and Polymerization by Transglutaminase 2 in Calcified Arteries of Matrix Gla Protein-deficient Mice","year":2006,"lang":"en","type":"article","venue":"Journal of Histochemistry & Cytochemistry","topic":"Bone and Dental Protein Studies","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Osteopontin; Tissue transglutaminase; Calcification; Matrix gla protein; Ectopic calcification; Chemistry; Western blot; Downregulation and upregulation; Extracellular matrix; Cell biology; Molecular biology; Pathology; Biochemistry; Biology; Enzyme; Endocrinology; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003477852,0.0010937,0.0005701866,0.001399015,0.0003519444,0.0006550134,0.0004575202,0.001124403,0.001568269],"category_scores_gemma":[0.0003112832,0.000803503,0.0006949297,0.0003338591,0.0008345069,0.000503212,0.0004823541,0.001413173,0.000518235],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004669146,"about_ca_system_score_gemma":0.0002869676,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004610344,"about_ca_topic_score_gemma":0.0007430802,"domain_scores_codex":[0.9995196,0.00007255823,0.00005645631,0.000164221,0.0001110836,0.00007612882],"domain_scores_gemma":[0.99905,0.00009833171,0.0004725926,0.00007718365,0.00004838295,0.0002536312],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004153488,0.00006258616,0.0003366814,0.00002792209,0.000008047086,0.0002158876,0.00003548381,0.00004391371,0.998208,0.0001179448,0.00001598063,0.0005121836],"study_design_scores_gemma":[0.0002737925,0.001470494,0.02656979,0.00003452791,0.000120359,0.002275367,0.0001353631,0.00152989,0.9653848,0.0003984238,0.001780538,0.00002662602],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950225,0.0007898047,0.002892535,0.0001013551,0.00002657798,0.00003234767,0.0003896736,0.000181081,0.000564181],"genre_scores_gemma":[0.9843037,0.001243201,0.007543739,0.000110902,0.00004368512,0.0002080385,0.0007149002,0.0001901209,0.00564187],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001568269,"threshold_uncertainty_score":0.005246341,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003325609847762189,"score_gpt":0.2264566197580074,"score_spread":0.2231310099102452,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}