{"id":"W2052584095","doi":"10.1002/ibd.20155","title":"Epithelial barrier disruption allows nondisease-causing bacteria to initiate and sustain IBD in the IL-10 gene-deficient mouse","year":2007,"lang":"en","type":"article","venue":"Inflammatory Bowel Diseases","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vernon Jubilee Hospital; University of Alberta","funders":"","keywords":"Inflammation; Biology; Immune system; Axenic; Microbiology; Immunology; Secretion; Microbiome; Bacteria; Gene; Intestinal mucosa; Bacteroides; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002443907,0.001049878,0.0004227772,0.001030386,0.000353901,0.0007149224,0.000546927,0.001166051,0.002631564],"category_scores_gemma":[0.0002159636,0.00045109,0.0005234203,0.0003238669,0.0006605507,0.0005545515,0.0004400711,0.001758204,0.000978832],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007069212,"about_ca_system_score_gemma":0.0004667728,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006463696,"about_ca_topic_score_gemma":0.001536389,"domain_scores_codex":[0.9995463,0.00005464888,0.00005776963,0.0001203127,0.0001141254,0.0001067087],"domain_scores_gemma":[0.9992576,0.00007622908,0.000321906,0.00007867286,0.00003290754,0.0002327499],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002158549,0.0001330382,0.0002163799,0.00003193711,0.000004618125,0.000078044,0.00001401018,0.00003331068,0.9987047,0.00008086883,0.00002509362,0.0004621088],"study_design_scores_gemma":[0.00006256188,0.001062295,0.00455927,0.00002908399,0.00002931699,0.000674608,0.00005178245,0.0004407391,0.9912235,0.00004765248,0.001811495,0.000007856458],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927146,0.001554333,0.002757552,0.0002131624,0.00005642157,0.00009704546,0.0008991687,0.0002451152,0.001462547],"genre_scores_gemma":[0.979903,0.001588169,0.007074641,0.0001855313,0.00003319668,0.0002364463,0.00154199,0.0001313991,0.009305575],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002631564,"threshold_uncertainty_score":0.008803487,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00899503583569898,"score_gpt":0.2609142796564961,"score_spread":0.2519192438207971,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}