{"id":"W2052588649","doi":"10.1159/000277660","title":"Insulin-Like Growth Factor-I Treatment in Primary Growth Hormone Insensitivity: Effect of Recombinant Human IGF-I (rhIGF-I) and rhIGF-I/rhIGF-Binding Protein-3 Complex","year":2010,"lang":"en","type":"article","venue":"Hormone Research in Paediatrics","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"Insmed; Ipsen; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Growth hormone receptor; Endocrinology; Internal medicine; Recombinant DNA; Growth factor; Medicine; Receptor; Hormone; Biology; Growth hormone; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002290693,0.0005344811,0.0008895471,0.0002197934,0.000387243,0.000191897,0.000295866,0.0004625127,0.002148136],"category_scores_gemma":[0.0002243847,0.0002016315,0.0005939606,0.0001470146,0.0005507798,0.0001069132,0.0001837571,0.000961055,0.000475546],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002284147,"about_ca_system_score_gemma":0.0002670883,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001117619,"about_ca_topic_score_gemma":0.001560564,"domain_scores_codex":[0.9998592,0.00003734853,0.00000975563,0.00003401998,0.00001939009,0.00004023486],"domain_scores_gemma":[0.999817,0.00003820032,0.0000154645,0.00001896779,0.00001194113,0.0000984701],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.03769125,0.00889264,0.004294402,0.0004551242,0.0003114537,0.004353846,0.0003289632,0.0004346078,0.9096694,0.00007270805,0.0007200233,0.03277551],"study_design_scores_gemma":[0.004054948,0.2356421,0.09495763,0.00005973447,0.0007174726,0.009818054,0.0002795924,0.001431192,0.6439286,0.0001101861,0.008948443,0.0000519562],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958869,0.002178887,0.0003878749,0.00008853764,0.00009865077,0.00009027658,0.00008295622,0.00003603479,0.001149917],"genre_scores_gemma":[0.996843,0.0007820993,0.0005580232,0.00008122597,0.00008181488,0.00005463269,0.0001777737,0.00001197679,0.001409515],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002148136,"threshold_uncertainty_score":0.007186174,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04881831738038019,"score_gpt":0.3249174750772907,"score_spread":0.2760991576969106,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}