{"id":"W2052591253","doi":"10.1093/neuonc/nou254.16","title":"EG-16 * ABERRANT Myst4/Brpf1 SIGNALING MISDIRECTS REGIONAL NEUROGENESIS PROGRAMS, SUSTAINING EXPRESSION OF SELF-RENEWAL GENES IN PEDIATRIC BRAIN CANCERS","year":2014,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Protein Degradation and Inhibitors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Hospital for Sick Children","funders":"","keywords":"Neurogenesis; Biology; Epigenetics; Chromatin; Neural stem cell; DNA methylation; Histone; Neural development; Cancer research; Genetics; Cell biology; Gene expression; Gene; Stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000121708,0.0002663039,0.000285595,0.0002956846,0.0001291846,0.0003183105,0.000205552,0.0002884706,0.001675674],"category_scores_gemma":[0.00009682468,0.0001415658,0.0002241016,0.0003037833,0.0002164875,0.0001959124,0.0002111072,0.0004841711,0.0005288505],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000359521,"about_ca_system_score_gemma":0.0002294028,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006535545,"about_ca_topic_score_gemma":0.0007176526,"domain_scores_codex":[0.999849,0.00001094539,0.00001849841,0.00003584585,0.00003589511,0.00004982944],"domain_scores_gemma":[0.9999306,0.000008479936,0.00002113929,0.00001295606,0.000005770733,0.00002115752],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001554837,0.00002166798,0.001666649,0.00003417517,0.00001440849,0.0003842746,0.00001793797,0.0001282778,0.9949402,0.0001526508,0.00012431,0.002360116],"study_design_scores_gemma":[0.00002022229,0.0001904898,0.02600889,0.000005768765,0.00004073027,0.004963146,0.00006933092,0.001001245,0.9610127,0.0001231457,0.006559198,0.000004971469],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956126,0.001007177,0.001193787,0.0000898457,0.00001914836,0.00001133711,0.0007427356,0.0001095991,0.001213839],"genre_scores_gemma":[0.993777,0.0007240299,0.001302371,0.00007979877,0.000005349413,0.00002037402,0.001203948,0.00003369239,0.002853352],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001675674,"threshold_uncertainty_score":0.005605638,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01447188031355788,"score_gpt":0.2625785312720758,"score_spread":0.2481066509585179,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}